IGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling

BACKGROUND: Glioblastomas (GBMs), the most common and most lethal of the primary brain tumors, are characterized by marked intra-tumor heterogeneity. Several studies have suggested that within these tumors a restricted population of chemoresistant glioma cells is responsible for recurrence. However,...

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Detalles Bibliográficos
Autores principales: Oliva, Claudia R., Halloran, Brian, Hjelmeland, Anita B., Vazquez, Ana, Bailey, Shannon M., Sarkaria, Jann N., Griguer, Corinne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148802/
https://www.ncbi.nlm.nih.gov/pubmed/30231881
http://dx.doi.org/10.1186/s12964-018-0273-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148802/
https://www.ncbi.nlm.nih.gov/pubmed/30231881
http://dx.doi.org/10.1186/s12964-018-0273-7

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