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IGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling

BACKGROUND: Glioblastomas (GBMs), the most common and most lethal of the primary brain tumors, are characterized by marked intra-tumor heterogeneity. Several studies have suggested that within these tumors a restricted population of chemoresistant glioma cells is responsible for recurrence. However,...

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Detalles Bibliográficos
Autores principales:	Oliva, Claudia R., Halloran, Brian, Hjelmeland, Anita B., Vazquez, Ana, Bailey, Shannon M., Sarkaria, Jann N., Griguer, Corinne E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148802/ https://www.ncbi.nlm.nih.gov/pubmed/30231881 http://dx.doi.org/10.1186/s12964-018-0273-7

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