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1,25(OH)(2)D(3) and dexamethasone additively suppress synovial fibroblast activation by CCR6(+) T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade

BACKGROUND: Despite recent improvements in the treatment of rheumatoid arthritis (RA), an insufficient treatment response and the development of treatment resistance in many patients illustrates the need for new therapeutic strategies. Chronic synovial inflammation could be suppressed by targeting R...

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Detalles Bibliográficos
Autores principales: Dankers, Wendy, González-Leal, Claudia, Davelaar, Nadine, Asmawidjaja, Patrick S., Mus, Adriana M. C., Hazes, Johanna M. W., Colin, Edgar M., Lubberts, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148958/
https://www.ncbi.nlm.nih.gov/pubmed/30236152
http://dx.doi.org/10.1186/s13075-018-1706-9

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