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1,25(OH)(2)D(3) and dexamethasone additively suppress synovial fibroblast activation by CCR6(+) T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade
BACKGROUND: Despite recent improvements in the treatment of rheumatoid arthritis (RA), an insufficient treatment response and the development of treatment resistance in many patients illustrates the need for new therapeutic strategies. Chronic synovial inflammation could be suppressed by targeting R...
Autores principales: | Dankers, Wendy, González-Leal, Claudia, Davelaar, Nadine, Asmawidjaja, Patrick S., Mus, Adriana M. C., Hazes, Johanna M. W., Colin, Edgar M., Lubberts, Erik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148958/ https://www.ncbi.nlm.nih.gov/pubmed/30236152 http://dx.doi.org/10.1186/s13075-018-1706-9 |
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