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The lncRNA CCAT1 upregulates TGFβR1 via sponging miR-490-3p to promote TGFβ1-induced EMT of ovarian cancer cells

BACKGROUND: Ovarian cancer is the fifth leading cause of cancer deaths in women worldwide. LncRNACCAT1 was reported to play a critical role in cell metastasis of ovarian cancer. However, little is known about the detailed mechanism of how CCAT1 enhances TGFβ1-induced EMT of ovarian cancer cells. MET...

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Detalles Bibliográficos
Autores principales: Mu, Yang, Li, Na, Cui, Yu-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148998/
https://www.ncbi.nlm.nih.gov/pubmed/30250403
http://dx.doi.org/10.1186/s12935-018-0604-1