Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

BACKGROUND: Defining the mechanisms that establish and regulate the transmission of epigenetic information from parent to offspring is critical for understanding disease heredity. Currently, the molecular pathways that regulate epigenetic information in the germline and its transmission to offspring...

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Detalles Bibliográficos
Autores principales: Stringer, Jessica M., Forster, Samuel C., Qu, Zhipeng, Prokopuk, Lexie, O’Bryan, Moira K., Gardner, David K., White, Stefan J., Adelson, David, Western, Patrick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149058/
https://www.ncbi.nlm.nih.gov/pubmed/30236109
http://dx.doi.org/10.1186/s12915-018-0569-5

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