A fluorescent methylation-switchable probe for highly sensitive analysis of FTO N(6)-methyladenosine demethylase activity in cells

N (6)-Methyladenosine (m(6)A) is one of the most abundant epigenetic modifications on mRNA. It is dynamically regulated by the m(6)A demethylases FTO and ALKBH5, which are currently attracting intense medical interest because of their strong association with several human diseases. Despite their cli...

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Detalles Bibliográficos
Autores principales: Cheong, Adeline, Low, Joanne J. A., Lim, Andrea, Yen, Paul M., Woon, Esther C. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149071/
https://www.ncbi.nlm.nih.gov/pubmed/30288236
http://dx.doi.org/10.1039/c8sc02163e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149071/
https://www.ncbi.nlm.nih.gov/pubmed/30288236
http://dx.doi.org/10.1039/c8sc02163e

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