Familial Carney complex with biatrial cardiac myxoma

We report a case of Carney complex (CNC) with biatrial cardiac myxoma. The patient had left and right atrial myxomas which were resected in a surgery. She showed bilateral adrenal tumors and multiple mammary tumors. She had pigmentation on her lower lip. Previously, her daughter was also diagnosed w...

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Detalles Bibliográficos
Autores principales: Takigami, Masao, Kawata, Masahito, Kintsu, Masayuki, Kodaira, Mutsuki, Sogabe, Koji, Kato, Yukinori, Matsuura, Takeshi, Kamemura, Kohei, Hirayama, Yasutaka, Adachi, Kazumasa, Matsuura, Akira, Sakamoto, Susumu, Tobe, Satoshi, Hamamoto, Kae, Kadoya, Manabu, Koyama, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese College of Cardiology 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149245/
https://www.ncbi.nlm.nih.gov/pubmed/30279766
http://dx.doi.org/10.1016/j.jccase.2016.12.007
Descripción
Sumario:We report a case of Carney complex (CNC) with biatrial cardiac myxoma. The patient had left and right atrial myxomas which were resected in a surgery. She showed bilateral adrenal tumors and multiple mammary tumors. She had pigmentation on her lower lip. Previously, her daughter was also diagnosed with CNC with cardiac myxoma. Both of them showed mutations in the PRKAR1A gene. <Learning objective: Carney complex is a syndrome with skin pigmentation, myxomas, and endocrine abnormalities. It is an autosomal dominant disease and shows PRKAR1A gene mutation. We experienced a rare case of familial Carney complex with biatrial cardiac myoxomas found by echocardiography and treated surgically.>

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