In Silico Identification and In Vitro Evaluation of Natural Inhibitors of Leishmania major Pteridine Reductase I

In a continuation of our computational efforts to find new natural inhibitors of a variety of target enzymes from parasites causing neglected tropical diseases (NTDs), we now report on 15 natural products (NPs) that we have identified as inhibitors of Leishmania major pteridine reductase I (LmPTR1)...

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Detalles Bibliográficos
Autores principales: Herrmann, Fabian C., Sivakumar, Nirina, Jose, Joachim, Costi, Maria P., Pozzi, Cecilia, Schmidt, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149668/
https://www.ncbi.nlm.nih.gov/pubmed/29211037
http://dx.doi.org/10.3390/molecules22122166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149668/
https://www.ncbi.nlm.nih.gov/pubmed/29211037
http://dx.doi.org/10.3390/molecules22122166

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