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In Silico Identification and In Vitro Evaluation of Natural Inhibitors of Leishmania major Pteridine Reductase I
In a continuation of our computational efforts to find new natural inhibitors of a variety of target enzymes from parasites causing neglected tropical diseases (NTDs), we now report on 15 natural products (NPs) that we have identified as inhibitors of Leishmania major pteridine reductase I (LmPTR1)...
Autores principales: | Herrmann, Fabian C., Sivakumar, Nirina, Jose, Joachim, Costi, Maria P., Pozzi, Cecilia, Schmidt, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149668/ https://www.ncbi.nlm.nih.gov/pubmed/29211037 http://dx.doi.org/10.3390/molecules22122166 |
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