ZMYND8 is a primary HIF coactivator that mediates breast cancer progression

Epigenetic regulator plays a pivotal role in breast cancer progression. We recently demonstrated that the epigenetic reader zinc finger MYND-type containing 8 (ZMYND8) mediates breast cancer progression and metastasis by activating hypoxia-inducible factor (HIF). This discovery provides new insights...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Wang, Yingfei, Luo, Weibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Author's Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149752/
https://www.ncbi.nlm.nih.gov/pubmed/30250924
http://dx.doi.org/10.1080/23723556.2018.1479619
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author Chen, Yan
Wang, Yingfei
Luo, Weibo
author_facet Chen, Yan
Wang, Yingfei
Luo, Weibo
author_sort Chen, Yan
collection PubMed
description Epigenetic regulator plays a pivotal role in breast cancer progression. We recently demonstrated that the epigenetic reader zinc finger MYND-type containing 8 (ZMYND8) mediates breast cancer progression and metastasis by activating hypoxia-inducible factor (HIF). This discovery provides new insights into the molecular mechanism underlying HIF activation and breast cancer progression.
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spelling pubmed-61497522019-08-01 ZMYND8 is a primary HIF coactivator that mediates breast cancer progression Chen, Yan Wang, Yingfei Luo, Weibo Mol Cell Oncol Author's Views Epigenetic regulator plays a pivotal role in breast cancer progression. We recently demonstrated that the epigenetic reader zinc finger MYND-type containing 8 (ZMYND8) mediates breast cancer progression and metastasis by activating hypoxia-inducible factor (HIF). This discovery provides new insights into the molecular mechanism underlying HIF activation and breast cancer progression. Taylor & Francis 2018-08-01 /pmc/articles/PMC6149752/ /pubmed/30250924 http://dx.doi.org/10.1080/23723556.2018.1479619 Text en © 2018 The Author(s). Published by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Author's Views
Chen, Yan
Wang, Yingfei
Luo, Weibo
ZMYND8 is a primary HIF coactivator that mediates breast cancer progression
title ZMYND8 is a primary HIF coactivator that mediates breast cancer progression
title_full ZMYND8 is a primary HIF coactivator that mediates breast cancer progression
title_fullStr ZMYND8 is a primary HIF coactivator that mediates breast cancer progression
title_full_unstemmed ZMYND8 is a primary HIF coactivator that mediates breast cancer progression
title_short ZMYND8 is a primary HIF coactivator that mediates breast cancer progression
title_sort zmynd8 is a primary hif coactivator that mediates breast cancer progression
topic Author's Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149752/
https://www.ncbi.nlm.nih.gov/pubmed/30250924
http://dx.doi.org/10.1080/23723556.2018.1479619
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AT wangyingfei zmynd8isaprimaryhifcoactivatorthatmediatesbreastcancerprogression
AT luoweibo zmynd8isaprimaryhifcoactivatorthatmediatesbreastcancerprogression

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