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Moving nuclear receptor Nur77 to damaged mitochondria for clearance by mitophagy
Selective clearance of damaged mitochondria can reverse pathological status in chronic inflammatory diseases. We recently identified a critical role of nuclear receptor Nur77 and celastrol in priming inflamed mitochondria for autophagy through its mitochondrial targeting and interaction with tumor n...
Autores principales: | Hu, Mengjie, Alitongbieke, Gulimiran, Su, Ying, Zhou, Hu, Zhang, Xiao-kun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149810/ https://www.ncbi.nlm.nih.gov/pubmed/30250883 http://dx.doi.org/10.1080/23723556.2017.1327005 |
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