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Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity

The fermentation and isolation of metabolites produced by an endophytic fungus, which was identified as Phomopsis sp. FJBR-11, based on phylogenetic analysis, led to the identification of six compounds, including dothiorelones A–C, and H, and cytosporones C and U. Among these compounds, cytosporone...

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Detalles Bibliográficos
Autores principales: Tan, Qing-Wei, Fang, Pei-Hua, Ni, Jian-Cheng, Gao, Fangluan, Chen, Qi-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149851/
https://www.ncbi.nlm.nih.gov/pubmed/29186928
http://dx.doi.org/10.3390/molecules22122073
Descripción
Sumario:The fermentation and isolation of metabolites produced by an endophytic fungus, which was identified as Phomopsis sp. FJBR-11, based on phylogenetic analysis, led to the identification of six compounds, including dothiorelones A–C, and H, and cytosporones C and U. Among these compounds, cytosporone U exhibited potent inhibitory activity against Tobacco mosaic virus (TMV). Moreover, the crude and a purified exopolysaccharide were proved to possess strong inhibitory effects against the virus infection.