Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity

The fermentation and isolation of metabolites produced by an endophytic fungus, which was identified as Phomopsis sp. FJBR-11, based on phylogenetic analysis, led to the identification of six compounds, including dothiorelones A–C, and H, and cytosporones C and U. Among these compounds, cytosporone...

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Autores principales: Tan, Qing-Wei, Fang, Pei-Hua, Ni, Jian-Cheng, Gao, Fangluan, Chen, Qi-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149851/
https://www.ncbi.nlm.nih.gov/pubmed/29186928
http://dx.doi.org/10.3390/molecules22122073
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author Tan, Qing-Wei
Fang, Pei-Hua
Ni, Jian-Cheng
Gao, Fangluan
Chen, Qi-Jian
author_facet Tan, Qing-Wei
Fang, Pei-Hua
Ni, Jian-Cheng
Gao, Fangluan
Chen, Qi-Jian
author_sort Tan, Qing-Wei
collection PubMed
description The fermentation and isolation of metabolites produced by an endophytic fungus, which was identified as Phomopsis sp. FJBR-11, based on phylogenetic analysis, led to the identification of six compounds, including dothiorelones A–C, and H, and cytosporones C and U. Among these compounds, cytosporone U exhibited potent inhibitory activity against Tobacco mosaic virus (TMV). Moreover, the crude and a purified exopolysaccharide were proved to possess strong inhibitory effects against the virus infection.
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spelling pubmed-61498512018-11-13 Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity Tan, Qing-Wei Fang, Pei-Hua Ni, Jian-Cheng Gao, Fangluan Chen, Qi-Jian Molecules Article The fermentation and isolation of metabolites produced by an endophytic fungus, which was identified as Phomopsis sp. FJBR-11, based on phylogenetic analysis, led to the identification of six compounds, including dothiorelones A–C, and H, and cytosporones C and U. Among these compounds, cytosporone U exhibited potent inhibitory activity against Tobacco mosaic virus (TMV). Moreover, the crude and a purified exopolysaccharide were proved to possess strong inhibitory effects against the virus infection. MDPI 2017-11-27 /pmc/articles/PMC6149851/ /pubmed/29186928 http://dx.doi.org/10.3390/molecules22122073 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tan, Qing-Wei
Fang, Pei-Hua
Ni, Jian-Cheng
Gao, Fangluan
Chen, Qi-Jian
Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity
title Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity
title_full Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity
title_fullStr Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity
title_full_unstemmed Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity
title_short Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity
title_sort metabolites produced by an endophytic phomopsis sp. and their anti-tmv activity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149851/
https://www.ncbi.nlm.nih.gov/pubmed/29186928
http://dx.doi.org/10.3390/molecules22122073
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AT gaofangluan metabolitesproducedbyanendophyticphomopsisspandtheirantitmvactivity
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