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Species-Specific Inactivation of Triosephosphate Isomerase from Trypanosoma brucei: Kinetic and Molecular Dynamics Studies

Human African Trypanosomiasis (HAT), a disease that provokes 2184 new cases a year in Sub-Saharan Africa, is caused by Trypanosoma brucei. Current treatments are limited, highly toxic, and parasite strains resistant to them are emerging. Therefore, there is an urgency to find new drugs against HAT....

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Detalles Bibliográficos
Autores principales:	Vázquez-Raygoza, Alejandra, Cano-González, Lucia, Velázquez-Martínez, Israel, Trejo-Soto, Pedro Josué, Castillo, Rafael, Hernández-Campos, Alicia, Hernández-Luis, Francisco, Oria-Hernández, Jesús, Castillo-Villanueva, Adriana, Avitia-Domínguez, Claudia, Sierra-Campos, Erick, Valdez-Solana, Mónica, Téllez-Valencia, Alfredo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149853/ https://www.ncbi.nlm.nih.gov/pubmed/29186784 http://dx.doi.org/10.3390/molecules22122055

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