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Low tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancer
PURPOSE: Tumor purity is defined as the proportion of cancer cells in the tumor tissue. The impact of tumor purity on colon cancer (CC) prognosis, genetic profile, and microenvironment has not been thoroughly accessed. MATERIALS AND METHODS: Clinical and transcriptomic data from three public dataset...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149864/ https://www.ncbi.nlm.nih.gov/pubmed/30271205 http://dx.doi.org/10.2147/CMAR.S171855 |