Low tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancer

PURPOSE: Tumor purity is defined as the proportion of cancer cells in the tumor tissue. The impact of tumor purity on colon cancer (CC) prognosis, genetic profile, and microenvironment has not been thoroughly accessed. MATERIALS AND METHODS: Clinical and transcriptomic data from three public dataset...

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Detalles Bibliográficos
Autores principales: Mao, Yihao, Feng, Qingyang, Zheng, Peng, Yang, Liangliang, Liu, Tianyu, Xu, Yuqiu, Zhu, Dexiang, Chang, Wenju, Ji, Meiling, Ren, Li, Wei, Ye, He, Guodong, Xu, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149864/
https://www.ncbi.nlm.nih.gov/pubmed/30271205
http://dx.doi.org/10.2147/CMAR.S171855

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