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MicroRNA-140-3p enhances the sensitivity of hepatocellular carcinoma cells to sorafenib by targeting pregnenolone X receptor

BACKGROUND: Pregnane X receptor (PXR), which is a member of the nuclear receptor protein family (nuclear receptor subfamily 1 group I member 2 [NR 1I2]), mediates the drug-resistance in the hepatocellular carcinoma (HCC) via enhancing the expression of drug-resistance-related genes which accelerate...

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Detalles Bibliográficos
Autores principales:	Li, Jiaqi, Zhao, Jing, Wang, Huan, Li, Xiaohan, Liu, Aixia, Qin, Qin, Li, Boan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149869/ https://www.ncbi.nlm.nih.gov/pubmed/30271172 http://dx.doi.org/10.2147/OTT.S179509

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