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Targeting endosomal pH for cancer chemotherapy
Altered pH homeostasis in cancer cells has been linked with essentially all classical hallmarks of cancer, including chemoresistance. We recently identified a conceptually novel mechanism for how dysregulated pH in hypoxic cells causes chemoresistance which is based on the aberrant cellular distribu...
Autores principales: | Lucien, Fabrice, Lavoie, Roxane R., Dubois, Claire M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149877/ https://www.ncbi.nlm.nih.gov/pubmed/30250892 http://dx.doi.org/10.1080/23723556.2018.1435184 |
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