Hydroboration-Oxidation of (±)-(1α,3α,3aβ,6aβ)-1,2,3,3a,4,6a-Hexahydro-1,3-pentalenedimethanol and Its O-Protected Derivatives: Synthesis of New Compounds Useful for Obtaining (iso)Carbacyclin Analogues and X-ray Analysis of the Products

Hydroboration-oxidation of 2α,4α-dimethanol-1β,5β-bicyclo[3.3.0]oct-6-en dibenzoate (1) gave alcohols 2 (symmetric) and 3 (unsymmetric) in ~60% yield, together with the monobenzoate diol 4a (37%), resulting from the reduction of the closer benzoate by the intermediate alkylborane. The corresponding...

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Detalles Bibliográficos
Autores principales: Tănase, Constantin I., Cocu, Florea G., Căproiu, Miron Teodor, Drăghici, Constantin, Shova, Sergiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149920/
https://www.ncbi.nlm.nih.gov/pubmed/29186795
http://dx.doi.org/10.3390/molecules22122032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149920/
https://www.ncbi.nlm.nih.gov/pubmed/29186795
http://dx.doi.org/10.3390/molecules22122032

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