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Intrinsic Disorder in Proteins with Pathogenic Repeat Expansions
Intrinsically disordered proteins and proteins with intrinsically disordered regions have been shown to be highly prevalent in disease. Furthermore, disease-causing expansions of the regions containing tandem amino acid repeats often push repetitive proteins towards formation of irreversible aggrega...
Autores principales: | Darling, April L., Uversky, Vladimir N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149999/ https://www.ncbi.nlm.nih.gov/pubmed/29186753 http://dx.doi.org/10.3390/molecules22122027 |
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