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Chemical Constituents from Euphorbia kansui
In this research, a new triterpenoid, tirucalla-8,24-diene-3β,11β-diol-7-one (1), and eupha-8,24-diene-3β,11β-diol-7-one (2), which was isolated from Euphorbia kansui for the first time, together with twelve other known compounds (3–14), were isolated from the ethyl acetate extract of Euphorbia kans...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150036/ https://www.ncbi.nlm.nih.gov/pubmed/29292735 http://dx.doi.org/10.3390/molecules22122176 |
| _version_ | 1783356920976900096 |
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| author | Zhang, Qiao Zhou, Qin-Rong Lou, Jian-Wei Chen, Pei-Dong Yao, Wei-Feng Tao, Wei-Wei Tang, Yu-Ping Dai, Guan-Cheng Wang, Kun Zhang, Li |
| author_facet | Zhang, Qiao Zhou, Qin-Rong Lou, Jian-Wei Chen, Pei-Dong Yao, Wei-Feng Tao, Wei-Wei Tang, Yu-Ping Dai, Guan-Cheng Wang, Kun Zhang, Li |
| author_sort | Zhang, Qiao |
| collection | PubMed |
| description | In this research, a new triterpenoid, tirucalla-8,24-diene-3β,11β-diol-7-one (1), and eupha-8,24-diene-3β,11β-diol-7-one (2), which was isolated from Euphorbia kansui for the first time, together with twelve other known compounds (3–14), were isolated from the ethyl acetate extract of Euphorbia kansui. Their structures were elucidated based on High resolution electrospray ionization mass spectrometry (HR-ESI-MS), Infrared Spectroscopy (IR), 1D and 2D Nuclear Magnetic Resonance (NMR) data. Both constituents 1 and 2 exhibited moderate cytotoxicity against colon cancer HCT-116, gastric cancer MKN-45 and breast cancer MCF-7. |
| format | Online Article Text |
| id | pubmed-6150036 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-61500362018-11-13 Chemical Constituents from Euphorbia kansui Zhang, Qiao Zhou, Qin-Rong Lou, Jian-Wei Chen, Pei-Dong Yao, Wei-Feng Tao, Wei-Wei Tang, Yu-Ping Dai, Guan-Cheng Wang, Kun Zhang, Li Molecules Article In this research, a new triterpenoid, tirucalla-8,24-diene-3β,11β-diol-7-one (1), and eupha-8,24-diene-3β,11β-diol-7-one (2), which was isolated from Euphorbia kansui for the first time, together with twelve other known compounds (3–14), were isolated from the ethyl acetate extract of Euphorbia kansui. Their structures were elucidated based on High resolution electrospray ionization mass spectrometry (HR-ESI-MS), Infrared Spectroscopy (IR), 1D and 2D Nuclear Magnetic Resonance (NMR) data. Both constituents 1 and 2 exhibited moderate cytotoxicity against colon cancer HCT-116, gastric cancer MKN-45 and breast cancer MCF-7. MDPI 2017-12-08 /pmc/articles/PMC6150036/ /pubmed/29292735 http://dx.doi.org/10.3390/molecules22122176 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Zhang, Qiao Zhou, Qin-Rong Lou, Jian-Wei Chen, Pei-Dong Yao, Wei-Feng Tao, Wei-Wei Tang, Yu-Ping Dai, Guan-Cheng Wang, Kun Zhang, Li Chemical Constituents from Euphorbia kansui |
| title | Chemical Constituents from Euphorbia kansui |
| title_full | Chemical Constituents from Euphorbia kansui |
| title_fullStr | Chemical Constituents from Euphorbia kansui |
| title_full_unstemmed | Chemical Constituents from Euphorbia kansui |
| title_short | Chemical Constituents from Euphorbia kansui |
| title_sort | chemical constituents from euphorbia kansui |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150036/ https://www.ncbi.nlm.nih.gov/pubmed/29292735 http://dx.doi.org/10.3390/molecules22122176 |
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