Cargando…

Antibacterial Activity of the Non-Cytotoxic Peptide (p-BthTX-I)(2) and Its Serum Degradation Product against Multidrug-Resistant Bacteria

Antimicrobial peptides can be used systemically, however, their susceptibility to proteases is a major obstacle in peptide-based therapeutic development. In the present study, the serum stability of p-BthTX-I (KKYRYHLKPFCKK) and (p-BthTX-I)(2), a p-BthTX-I disulfide-linked dimer, were analyzed by ma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santos-Filho, Norival A., Fernandes, Rafaela S., Sgardioli, Bruna F., Ramos, Matheus A. S., Piccoli, Julia P., Camargo, Ilana L. B. C., Bauab, Tais M., Cilli, Eduardo M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150245/ https://www.ncbi.nlm.nih.gov/pubmed/29113051 http://dx.doi.org/10.3390/molecules22111898

Ejemplares similares

Effects of Dimerization, Dendrimerization, and Chirality in p-BthTX-I Peptide Analogs on the Antibacterial Activity and Enzymatic Inhibition of the SARS-CoV-2 PL(pro) Protein
por: Bitencourt, Natália Vitória, et al.
Publicado: (2023)

Linear B-cell epitopes in BthTX-I, BthTX-II and BthA-I, phospholipase A(2's )from Bothrops jararacussu snake venom, recognized by therapeutically neutralizing commercial horse antivenom
por: De-Simone, Salvatore, et al.
Publicado: (2014)

BthTX-I from Bothrops jararacussu induces apoptosis in human breast cancer cell lines and decreases cancer stem cell subpopulation
por: Bezerra, Patrícia Heloise Alves, et al.
Publicado: (2019)

Antitumor potential of the myotoxin BthTX-I from Bothrops jararacussu snake venom: evaluation of cell cycle alterations and death mechanisms induced in tumor cell lines
por: Prinholato da Silva, Cássio, et al.
Publicado: (2015)

A New Approach to Inhibiting Triple-Negative Breast Cancer: In Vitro, Ex Vivo and In Vivo Antiangiogenic Effect of BthTx-II, a PLA(2)-Asp-49 from Bothrops jararacussu Venom
por: Van Petten de Vasconcelos Azevedo, Fernanda, et al.
Publicado: (2022)

Dimerization of Antimicrobial Peptides: A Promising Strategy to Enhance Antimicrobial Peptide Activity
por: Lorenzon, Esteban N., et al.
Publicado: (2019)

Antimicrobial activity of natural products against Helicobacter pylori: a review
por: Bonifácio, Bruna Vidal, et al.
Publicado: (2014)

What’s in a Name? Michael N. Marsh, BTh, DPhil, DM, DSc, FRCP
por: Ensari, Arzu
Publicado: (2021)

The prevalence of disability and associated factors among community adults in the baseline of CHCN-BTH Cohort Study
por: Zhu, Hui-Ping, et al.
Publicado: (2023)

Taking Action on Air Pollution Control in the Beijing-Tianjin-Hebei (BTH) Region: Progress, Challenges and Opportunities
por: Wang, Li, et al.
Publicado: (2018)

BTH Treatment Delays the Senescence of Postharvest Pitaya Fruit in Relation to Enhancing Antioxidant System and Phenylpropanoid Pathway
por: Ding, Xiaochun, et al.
Publicado: (2021)

Preventing autosomal-dominant hearing loss in Bth mice with CRISPR/CasRx-based RNA editing
por: Zheng, Ziwen, et al.
Publicado: (2022)

Nanotechnology-based drug delivery systems and herbal medicines: a review
por: Bonifácio, Bruna Vidal, et al.
Publicado: (2013)

Activity, specificity and structure of I-Bth0305I: a representative of a new homing endonuclease family
por: Taylor, Gregory K., et al.
Publicado: (2011)

Temperature-Dependent Affinity Changes in Substrate Binding Affect the Cleavage Activity of BthC2c1
por: Wu, Dan, et al.
Publicado: (2023)

Cytotoxic and pro-apoptotic action of MjTX-I, a phospholipase A2 isolated from Bothrops moojeni snake venom, towards leukemic cells
por: Benati, Rogério Bodini, et al.
Publicado: (2018)

Spatial Variation of the Effect of Multidimensional Urbanization on PM(2.5) Concentration in the Beijing–Tianjin–Hebei (BTH) Urban Agglomeration
por: Huang, Qianyuan, et al.
Publicado: (2021)

Transcriptome sequencing and differential expression analysis of natural and BTH-treated wound healing in potato tubers (Solanum tuberosum L.)
por: Jiang, Hong, et al.
Publicado: (2022)

Esterilidad femenina Dx. y Tx. /
por: Jiménez Jácome, José Alfredo
Publicado: (1987)

A curcumin-loaded liquid crystal precursor mucoadhesive system for the treatment of vaginal candidiasis
por: Salmazi, Rafael, et al.
Publicado: (2015)

Cloning and expression analysis of cDNAs corresponding to genes activated in cucumber showing systemic acquired resistance after BTH treatment
por: Bovie, Catherine, et al.
Publicado: (2004)

Serum lipoprotein (a) associates with the risk of renal function damage in the CHCN-BTH Study: Cross-sectional and Mendelian randomization analyses
por: Xie, Yunyi, et al.
Publicado: (2022)

Utilizing differences in bTH tolerance between the parents of two-line hybrid rice to improve the purity of hybrid rice seed
por: Zhang, Xiuli, et al.
Publicado: (2023)

Degradation kinetics of α‐conotoxin TxID
por: Xu, Pan, et al.
Publicado: (2019)

A Nanostructured Lipid System as a Strategy to Improve the in Vitro Antibacterial Activity of Copper(II) Complexes
por: da Silva, Patricia B., et al.
Publicado: (2015)

The CSF of normal H-Tx rats promotes neuronal differentiation from neurospheres but CSF of hydrocephalic H-Tx rats does not
por: González, César, et al.
Publicado: (2006)

Selective sorption of PAHs from TX100 solution by resin SP850: effects of TX100 concentrations and PAHs solubility
por: Zeng, Yaxiong, et al.
Publicado: (2021)

Sonochemical One-Step Synthesis of Polymer-Capped Metal Oxide Nanocolloids: Antibacterial Activity and Cytotoxicity
por: Nagvenkar, Anjani P., et al.
Publicado: (2019)

Nanotechnological strategies for systemic microbial infections treatment: A review
por: dos Santos Ramos, Matheus Aparecido, et al.
Publicado: (2020)

Genomic Analysis of the Recent Viral Isolate vB_BthP-Goe4 Reveals Increased Diversity of φ29-Like Phages
por: Schilling, Tobias, et al.
Publicado: (2018)

Elevated lipoprotein(a) and risk of coronary heart disease according to different lipid profiles in the general Chinese community population: the CHCN-BTH study
por: Guo, Chunyue, et al.
Publicado: (2021)

Elevated lipoprotein(a) and risk of coronary heart disease according to different lipid profiles in the general Chinese community population: the CHCN-BTH study
por: Hu, Yong, et al.
Publicado: (2021)

(t)tX (X=anything but H) Production on ATLAS
por: Johns, Kenneth
Publicado: (2022)

DSPE-PEG Modification of α-Conotoxin TxID
por: Zhao, Weinan, et al.
Publicado: (2019)

Liquid crystal precursor mucoadhesive system as a strategy to improve the prophylactic action of Syngonanthus nitens (Bong.) Ruhland against infection by Candida krusei
por: dos Santos Ramos, Matheus Aparecido, et al.
Publicado: (2015)

A Novel DFNA36 Mutation in TMC1 Orthologous to the Beethoven (Bth) Mouse Associated with Autosomal Dominant Hearing Loss in a Chinese Family
por: Zhao, Yali, et al.
Publicado: (2014)

Response of cross-correlations between high PM(2.5) and O(3) with increasing time scales to the COVID-19: different trends in BTH and PRD
por: Bao, Bingyi, et al.
Publicado: (2023)

Presynaptic Proteins as Markers of the Neurotoxic Activity of BmjeTX-I and BmjeTX-II Toxins from Bothrops marajoensis (Marajó Lancehead) Snake Venom
por: Lisboa, Antonio, et al.
Publicado: (2016)

Composition-Dependent Cytotoxic and Antibacterial Activity of Biopolymer-Capped Ag/Au Bimetallic Nanoparticles against Melanoma and Multidrug-Resistant Pathogens
por: Nieto-Argüello, Alfonso, et al.
Publicado: (2022)

In Vitro Antibacterial Potential against Multidrug-Resistant Salmonella, Cytotoxicity, and Acute Biochemical Effects in Mice of Annona muricata Leaf Extracts
por: Ngemenya, Moses Njutain, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1fr4ihtmg5ln43kb6t1umh1khr