Cargando…

Oleanolic Acid and Its Derivatives: Biological Activities and Therapeutic Potential in Chronic Diseases

The increasing demand for natural products as an alternative therapy for chronic diseases has encouraged research into the pharmacological importance of bioactive compounds from plants. Recently, there has been a surge of interest in the therapeutic potential of oleanolic acid (OA) in the prevention...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ayeleso, Taiwo Betty, Matumba, Mashudu Given, Mukwevho, Emmanuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150249/ https://www.ncbi.nlm.nih.gov/pubmed/29137205 http://dx.doi.org/10.3390/molecules22111915

Ejemplares similares

Long-Term Impact of Neonatal Intake of Oleanolic Acid on the Expression of AMP-Activated Protein Kinase, Adiponectin and Inflammatory Cytokines in Rats Fed with a High Fructose Diet
por: Matumba, Mashudu Given, et al.
Publicado: (2019)

A Study on Neonatal Intake of Oleanolic Acid and Metformin in Rats (Rattus norvegicus) with Metabolic Dysfunction: Implications on Lipid Metabolism and Glucose Transport
por: Molepo, Mmahiine, et al.
Publicado: (2018)

Aqueous-Methanol Extracts of Orange-Fleshed Sweet Potato (Ipomoea batatas) Ameliorate Oxidative Stress and Modulate Type 2 Diabetes Associated Genes in Insulin Resistant C2C12 Cells
por: Ayeleso, Taiwo Betty, et al.
Publicado: (2018)

Short-Term Neonatal Oral Administration of Oleanolic Acid Protects against Fructose-Induced Oxidative Stress in the Skeletal Muscles of Suckling Rats
por: Nyakudya, Trevor Tapiwa, et al.
Publicado: (2019)

Potential Role of Sulfur-Containing Antioxidant Systems in Highly Oxidative Environments
por: Mukwevho, Emmanuel, et al.
Publicado: (2014)

The long‐term protective effects of neonatal administration of curcumin against nonalcoholic steatohepatitis in high‐fructose‐fed adolescent rats
por: Ibrahim, Kasimu G., et al.
Publicado: (2019)

Ameliorative Potential of Hydroethanolic Leaf Extract of Parquetina nigrescens on d-Galactose-Induced Testicular Injury
por: Ajayi, Lydia, et al.
Publicado: (2021)

The protective effect of neonatal oral administration of oleanolic acid against the subsequent development of fructose-induced metabolic dysfunction in male and female rats
por: Nyakudya, Trevor T., et al.
Publicado: (2018)

Prophylactic and therapeutic roles of oleanolic acid and its derivatives in several diseases
por: Sen, Alaattin
Publicado: (2020)

Metabolomics: A Scoping Review of Its Role as a Tool for Disease Biomarker Discovery in Selected Non-Communicable Diseases
por: Aderemi, Adewale Victor, et al.
Publicado: (2021)

Oleanolic Acid: Extraction, Characterization and Biological Activity
por: Castellano, José M., et al.
Publicado: (2022)

Development and Evaluation of Oleanolic Acid Dosage Forms and Its Derivatives
por: Feng, Anjie, et al.
Publicado: (2020)

Antiviral Activities of Oleanolic Acid and Its Analogues
por: Khwaza, Vuyolwethu, et al.
Publicado: (2018)

Antioxidant Strategies in the Management of Diabetic Neuropathy
por: Oyenihi, Ayodeji Babatunde, et al.
Publicado: (2015)

Evaluation of free radical scavenging capacity of methoxy containing-hybrids of thiosemicarbazone-triazole and their influence on glucose transport
por: Ayeleso, Ademola O., et al.
Publicado: (2018)

Antiprotozoal Activity of Triazole Derivatives of Dehydroabietic Acid and Oleanolic Acid
por: Pertino, Mariano Walter, et al.
Publicado: (2017)

Harnessing Oleanolic Acid and Its Derivatives as Modulators of Metabolic Nuclear Receptors
por: Radwan, Mohamed O., et al.
Publicado: (2023)

Anti-Cancer Potential of Synthetic Oleanolic Acid Derivatives and Their Conjugates with NSAIDs
por: Baer-Dubowska, Wanda, et al.
Publicado: (2021)

Design, Synthesis, Molecular Modelling, and Biological Evaluation of Oleanolic Acid-Arylidene Derivatives as Potential Anti-Inflammatory Agents
por: Hassan Mir, Reyaz, et al.
Publicado: (2021)

Hypoxia Imaging and Biological Evaluation of the Radiosensitizing Effect of Oleanolic Acid
por: Wang, Hui, et al.
Publicado: (2018)

Synthesis and biological evaluations of oleanolic acid indole derivatives as hyaluronidase inhibitors with enhanced skin permeability
por: He, Hao, et al.
Publicado: (2021)

Ursolic and Oleanolic Acids: Plant Metabolites with Neuroprotective Potential
por: Gudoityte, Evelina, et al.
Publicado: (2021)

Oleanolic Acid Complexation with Cyclodextrins Improves Its Cell Bio-Availability and Biological Activities for Cell Migration
por: Stelling-Férez, Javier, et al.
Publicado: (2023)

Amino Acid Derivatives of Ligustrazine-Oleanolic Acid as New Cytotoxic Agents
por: Chu, Fuhao, et al.
Publicado: (2014)

Oleanolic acid ethanol monosolvate
por: Froelich, Anna, et al.
Publicado: (2010)

The Synergistic Biologic Activity of Oleanolic and Ursolic Acids in Complex with Hydroxypropyl-γ-Cyclodextrin
por: Soica, Codruţa, et al.
Publicado: (2014)

Design and preparation of derivatives of oleanolic and glycyrrhetinic acids with cytotoxic properties
por: Wang, Rui, et al.
Publicado: (2018)

Biological Activity of Oleanolic Acid Derivatives HIMOXOL and Br-HIMOLID in Breast Cancer Cells Is Mediated by ER and EGFR
por: Lisiak, Natalia, et al.
Publicado: (2023)

Antimicrobial Activity of Oleanolic and Ursolic Acids: An Update
por: Jesus, Jéssica A., et al.
Publicado: (2015)

Hybrid Compounds Strategy in the Synthesis of Oleanolic Acid Skeleton-NSAID Derivatives
por: Pawełczyk, Anna, et al.
Publicado: (2016)

Oleanolic Acid-amino Acids Derivatives: Design, Synthesis, and Hepatoprotective Evaluation In Vitro and In Vivo
por: Chu, Fuhao, et al.
Publicado: (2018)

1,2,3-Triazole-Substituted Oleanolic Acid Derivatives: Synthesis and Antiproliferative Activity
por: Pertino, Mariano Walter, et al.
Publicado: (2013)

Mechanistic investigations of antitumor activity of a Rhodamine B-oleanolic acid derivative bioconjugate
por: Macașoi, Ioana, et al.
Publicado: (2020)

Mechanistic investigations of antitumor activity of a Rhodamine B-oleanolic acid derivative bioconjugate
por: Macașoi, Ioana, et al.
Publicado: (2021)

Synthesis and Biological Evaluation of Oleanolic Acid Derivatives as Selective Vascular Endothelial Growth Factor Promoter i-Motif Ligands
por: Zeng, Huang, et al.
Publicado: (2021)

An Oleanolic Acid Derivative Inhibits Hemagglutinin-Mediated Entry of Influenza A Virus
por: Ye, Mengdie, et al.
Publicado: (2020)

Enhancement of Platelet Aggregation by Ursolic Acid and Oleanolic Acid
por: Kim, Mikyung, et al.
Publicado: (2014)

Recent advances in nanoparticle formulation of oleanolic acid
por: Chen, Meiwan, et al.
Publicado: (2011)

Facile Synthesis of Oleanolic Acid Monoglycosides and Diglycosides
por: Sha, Yu, et al.
Publicado: (2008)

Conjugation of Diclofenac with Novel Oleanolic Acid Derivatives Modulate Nrf2 and NF-κB Activity in Hepatic Cancer Cells and Normal Hepatocytes Leading to Enhancement of Its Therapeutic and Chemopreventive Potential
por: Narożna, Maria, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pl736lb6onea6qd0khtfrtf8j7