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Synthesis of Substituted Oxo-Azepines by Regio- and Diastereoselective Hydroxylation

Substituted seven-membered N-heterocycles are prevalent bioactive epitopes and useful synthons for preparing enzyme inhibitors or molecular recognition systems. To fully exploit the chemical properties of this flexible N-heterocycle scaffold, efficient methods for its diverse functionalization are r...

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Detalles Bibliográficos
Autores principales: Spedding, Harold, Karuso, Peter, Liu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150284/
https://www.ncbi.nlm.nih.gov/pubmed/29088108
http://dx.doi.org/10.3390/molecules22111871