Cargando…

Syntheses of Novel 4-Substituted N-(5-amino-1H-1,2,4-triazol-3-yl)pyridine-3-sulfonamide Derivatives with Potential Antifungal Activity

Candidiasis represent a serious threat for patients with altered immune responses. Therefore, we have undertaken the synthesis of compounds comprising a pyridine-3-sulfonamide scaffold and known antifungally active 1,2,4-triazole substituents. Thus a series of novel 4-substituted N-(5-amino-1H-1,2,4...

Descripción completa

Detalles Bibliográficos
Autores principales:	Szafrański, Krzysztof, Sławiński, Jarosław, Kędzia, Anna, Kwapisz, Ewa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150321/ https://www.ncbi.nlm.nih.gov/pubmed/29112162 http://dx.doi.org/10.3390/molecules22111926

Ejemplares similares

Synthesis of Novel 1-(4-Substituted pyridine-3-sulfonyl)-3-phenylureas with Potential Anticancer Activity
por: Szafrański, Krzysztof, et al.
Publicado: (2015)

Synthesis, Characterization and Antifungal Evaluation of 5-Substituted-4-Amino-1,2,4-Triazole-3-Thioesters
por: Hasan, Aurangzeb, et al.
Publicado: (2011)

Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1,2,4-Triazoles
por: Colanceska-Ragenovic, Katica, et al.
Publicado: (2001)

Inhibition studies of Brucella suis β-carbonic anhydrases with a series of 4-substituted pyridine-3-sulphonamides
por: Monti, Simona Maria, et al.
Publicado: (2017)

5-(Pyridin-2-yl)-3,3′-bi(1H-1,2,4-triazole)
por: Xu, Zhouqing, et al.
Publicado: (2011)

3-Pyridin-2-yl-1H-1,2,4-triazol-5-amine
por: Dolzhenko, Anton V., et al.
Publicado: (2008)

Synthesis and molecular structure of novel 2-(alkylthio)-4-chloro-N-(4,5-dihydro-5-oxo-1H-1,2,4-triazol-3-yl)-5-methylbenzenesulfonamides with potential anticancer activity
por: Sławiński, Jarosław, et al.
Publicado: (2012)

Thermal Rearrangement of Allyl Substituted Unsymmetric 4H-1,2,4-Triazoles to the Corresponding 1H-1,2,4-triazoles.
por: Jørgensen, Kåre B., et al.
Publicado: (2001)

2,2′-(4-Methyl-4H-1,2,4-triazole-3,5-diyl)dibenzenesulfonamide
por: Akhtar, Tasleem, et al.
Publicado: (2012)

5-Amino-3-(4H-1,2,4-triazol-4-yl)-1H-1,2,4-triazole
por: Liu, Bing, et al.
Publicado: (2012)

Regioselectivity of the alkylation of S-substituted 1,2,4-triazoles with dihaloalkanes
por: Boraei, Ahmed T. A., et al.
Publicado: (2016)

Novel 5-Substituted 2-(Aylmethylthio)-4-chloro-N-(5-aryl-1,2,4-triazin-3-yl)benzenesulfonamides: Synthesis, Molecular Structure, Anticancer Activity, Apoptosis-Inducing Activity and Metabolic Stability
por: Żołnowska, Beata, et al.
Publicado: (2016)

Synthesis of Novel Pyrido[4,3-e][1,2,4]triazino[3,2-c][1,2,4]thiadiazine 6,6-dioxide Derivatives with Potential Anticancer Activity
por: Sławiński, Jarosław, et al.
Publicado: (2015)

Anti-inflammatory and antinociceptive evaluation of newly synthesized 4-(substituted ethanoyl) amino-3-mercapto-5-(4-methoxy) phenyl-1,2,4-triazoles
por: Upmanyu, Neeraj, et al.
Publicado: (2011)

2-(5-{6-[5-(Pyrazin-2-yl)-1H-1,2,4-triazol-3-yl]pyridin-2-yl}-1H-1,2,4-triazol-3-yl)pyrazine
por: Xu, Zhouqing, et al.
Publicado: (2011)

N-(5-Amino-1H-1,2,4-triazol-3-yl)pyridine-2-carboxamide
por: Hernández-Gil, Javier, et al.
Publicado: (2013)

Syntheses and crystal structures of two adamantyl-substituted 1,2,4-triazole-5-thione N-Mannich bases
por: Al-Alshaikh, Monirah A., et al.
Publicado: (2017)

Synthesis, antifungal and antibacterial activity of novel 1,2,4-triazole derivatives
por: Gupta, Deepa, et al.
Publicado: (2015)

1H-1,2,4-Triazole-3-carboxamide
por: Xie, Qing-Ruo
Publicado: (2008)

3-Nitro-1H-1,2,4-triazole
por: Hemamalini, Madhukar, et al.
Publicado: (2010)

2,6-Bis(4H-1,2,4-triazol-4-yl)pyridine dihydrate
por: Liu, Shang Yuan, et al.
Publicado: (2011)

2,6-Bis(4H-1,2,4-triazol-4-yl)pyridine dihydrate
por: Jiao, De-quan, et al.
Publicado: (2011)

4-[(3-Nitrobenzylidene)amino]-3-(pyridin-4-yl)-1H-1,2,4-triazole-5(4H)-thione
por: Li, Tian-Bao, et al.
Publicado: (2012)

Electrocatalytic CO(2) Reduction by [Re(CO)(3)Cl(3-(pyridin-2-yl)-5-phenyl-1,2,4-triazole)] and [Re(CO)(3)Cl(3-(2-pyridyl)-1,2,4-triazole)]
por: Nguyen, Phuong N., et al.
Publicado: (2022)

Synthesis and Anti-Yeast Evaluation of Novel 2-Alkylthio-4-chloro-5-methyl-N-[imino-(1-oxo-(1H)-phthalazin-2-yl)methyl]benzenesulfonamide Derivatives
por: Sławiński, Jarosław, et al.
Publicado: (2014)

[Hydrogen bis(1,2,4-triazole)] 1,2,4-triazolium bis(3-carboxy-4-hydroxybenzenesulfonate) 1,2,4-triazole disolvate
por: Qiu, Ming-qiang
Publicado: (2010)

N-(1H-1,2,4-Triazol-5-yl)pyridine-2-carboxamide
por: Miao, Jing, et al.
Publicado: (2009)

3-Phenyl-1H-1,2,4-triazol-5-amine–5-phenyl-1H-1,2,4-triazol-3-amine (1/1)
por: Dolzhenko, Anton V., et al.
Publicado: (2008)

Synthesis and Pharmacological Activities of Some New 3-Substituted-4-Amino-5-Mercapto-1,2,4-Triazoles
por: Desai, Shobha R., et al.
Publicado: (2011)

Synthesis, Antitumor Evaluation, Molecular Modeling and Quantitative Structure–Activity Relationship (QSAR) of Novel 2-[(4-Amino-6-N-substituted-1,3,5-triazin-2-yl)methylthio]-4-chloro-5-methyl-N-(1H-benzo[d]imidazol-2(3H)-ylidene)Benzenesulfonamides
por: Tomorowicz, Łukasz, et al.
Publicado: (2020)

4-[(2-Bromobenzylidene)amino]-3-(pyridin-4-yl)-1H-1,2,4-triazole-5(4H)-thione
por: Gao, Wei, et al.
Publicado: (2012)

Synthesis and Antifungal Activity of Novel Myrtenal-Based 4-Methyl-1,2,4-triazole-thioethers
por: Lin, Gui-Shan, et al.
Publicado: (2017)

Microwave Assistant Synthesis, Antifungal Activity and DFT Theoretical Study of Some Novel 1,2,4-Triazole Derivatives Containing Pyridine Moiety
por: Sun, Guo-Xiang, et al.
Publicado: (2014)

Bis(4H-1,2,4-triazol-3-yl)disulfane
por: Liu, Dongsheng, et al.
Publicado: (2007)

4-{3-[Hydroxy(phenyl)methyl]-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-4-yl}benzenesulfonamide
por: Akkurt, Mehmet, et al.
Publicado: (2010)

4-Amino-3,5-dimethyl-4H-1,2,4-triazole
por: Li, Daojin, et al.
Publicado: (2008)

Synthesis and Screening of New [1,3,4]Oxadiazole, [1,2,4]Triazole, and [1,2,4]Triazolo[4,3-b][1,2,4]triazole Derivatives as Potential Antitumor Agents on the Colon Carcinoma Cell Line (HCT-116)
por: Abdelrehim, El-sayed M.
Publicado: (2021)

Synthesis, antimicrobial, and anti-inflammatory activity, of novel S-substituted and N-substituted 5-(1-adamantyl)-1,2,4-triazole-3-thiols
por: Al-Abdullah, Ebtehal S, et al.
Publicado: (2014)

4-(1,2,4-Triazol-1-yl)aniline
por: Fun, Hoong-Kun, et al.
Publicado: (2010)

Crystal structures of 2,6-bis[(1H-1,2,4-triazol-1-yl)methyl]pyridine and 1,1-[pyridine-2,6-diylbis(methylene)]bis(4-methyl-1H-1,2,4-triazol-4-ium) iodide triiodide
por: Guino-o, Marites A., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_h9vc2ta23keu15g6r5era1uib0