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New 2-Phenylthiazoles as Potential Sortase A Inhibitors: Synthesis, Biological Evaluation and Molecular Docking

Sortase A inhibition is a well establish strategy for decreasing bacterial virulence by affecting numerous key processes that control biofilm formation, host cell entry, evasion and suppression of the immune response and acquisition of essential nutrients. A meta-analysis of structures known to act...

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Detalles Bibliográficos
Autores principales: Oniga, Smaranda Dafina, Araniciu, Cătălin, Palage, Mariana Doina, Popa, Marcela, Chifiriuc, Mariana Carmen, Marc, Gabriel, Pirnau, Adrian, Stoica, Cristina Ioana, Lagoudis, Ioannis, Dragoumis, Theodoros, Oniga, Ovidiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150342/
https://www.ncbi.nlm.nih.gov/pubmed/29077016
http://dx.doi.org/10.3390/molecules22111827