Non-Covalent Loading of Anti-Cancer Doxorubicin by Modularizable Peptide Self-Assemblies for a Nanoscale Drug Carrier

We prepared nanoscale, modularizable, self-assembled peptide nanoarchitectures with diameters less of than 20 nm by combining β-sheet-forming peptides tethering a cell-penetrating peptide or a nuclear localization signal sequence. We also found that doxorubicin (Dox), an anti-cancer drug, was non-co...

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Detalles Bibliográficos
Autores principales: Tomizaki, Kin-ya, Kishioka, Kohei, Kataoka, Shunsuke, Miyatani, Makoto, Ikeda, Takuya, Komada, Mami, Imai, Takahito, Usui, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150382/
https://www.ncbi.nlm.nih.gov/pubmed/29113134
http://dx.doi.org/10.3390/molecules22111916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150382/
https://www.ncbi.nlm.nih.gov/pubmed/29113134
http://dx.doi.org/10.3390/molecules22111916

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