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Non-Covalent Loading of Anti-Cancer Doxorubicin by Modularizable Peptide Self-Assemblies for a Nanoscale Drug Carrier
We prepared nanoscale, modularizable, self-assembled peptide nanoarchitectures with diameters less of than 20 nm by combining β-sheet-forming peptides tethering a cell-penetrating peptide or a nuclear localization signal sequence. We also found that doxorubicin (Dox), an anti-cancer drug, was non-co...
Autores principales: | Tomizaki, Kin-ya, Kishioka, Kohei, Kataoka, Shunsuke, Miyatani, Makoto, Ikeda, Takuya, Komada, Mami, Imai, Takahito, Usui, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150382/ https://www.ncbi.nlm.nih.gov/pubmed/29113134 http://dx.doi.org/10.3390/molecules22111916 |
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