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Design, Synthesis, and Evaluation of Novel Phenolic Acid/Dipeptide/Borneol Hybrids as Potent Angiotensin Converting Enzyme (ACE) Inhibitors with Anti-hypertension Activity

Under the guidance of combination of traditional Chinese medicine chemistry (CTCMC), this study describes the preparation of a phenolic acid/dipeptide/borneol hybrid consisting of phenolic acid and a bornyl moiety connected to the dipeptide N-terminal and C-terminal respectively. It also evaluates t...

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Detalles Bibliográficos
Autores principales: Sun, Ying, Bai, Yujun, He, Xirui, Bai, Yajun, Liu, Pei, Zhao, Zefeng, Chen, Xufei, Zheng, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150412/
https://www.ncbi.nlm.nih.gov/pubmed/29099799
http://dx.doi.org/10.3390/molecules22111739