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An enriched environment prevents diabetes-induced cognitive impairment in rats by enhancing exosomal miR-146a secretion from endogenous bone marrow-derived mesenchymal stem cells
Increasing evidence suggests that an enriched environment (EE) ameliorates cognitive impairment by promoting repair of brain damage. However, the mechanisms by which this occurs have not been determined. To address this issue, we investigated whether an EE enhanced the capability of endogenous bone...
Autores principales: | Kubota, Kenta, Nakano, Masako, Kobayashi, Eiji, Mizue, Yuka, Chikenji, Takako, Otani, Miho, Nagaishi, Kanna, Fujimiya, Mineko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150479/ https://www.ncbi.nlm.nih.gov/pubmed/30240403 http://dx.doi.org/10.1371/journal.pone.0204252 |
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