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Activation of RHO-1 in cholinergic motor neurons competes with dopamine signalling to control locomotion

The small GTPase RhoA plays a crucial role in the regulation of neuronal signalling to generate behaviour. In the developing nervous system RhoA is known to regulate the actin cytoskeleton, however the effectors of RhoA-signalling in adult neurons remain largely unidentified. We have previously show...

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Detalles Bibliográficos
Autores principales: Essmann, Clara L., Ryan, Katie R., Elmi, Muna, Bryon-Dodd, Kimberley, Porter, Andrew, Vaughan, Andrew, McMullan, Rachel, Nurrish, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150489/
https://www.ncbi.nlm.nih.gov/pubmed/30240421
http://dx.doi.org/10.1371/journal.pone.0204057