RNA capping by mitochondrial and multi-subunit RNA polymerases

Recently, it was found that bacterial and eukaryotic transcripts are capped with cellular cofactors installed by their respective RNA polymerases (RNAPs) during transcription initiation. We now show that mitochondrial RNAP efficiently caps transcripts with ADP – containing cofactors. However, a func...

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Detalles Bibliográficos
Autores principales: Julius, Christina, Riaz-Bradley, Amber, Yuzenkova, Yulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Point-of-View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150613/
https://www.ncbi.nlm.nih.gov/pubmed/29624107
http://dx.doi.org/10.1080/21541264.2018.1456258
Descripción
Sumario:Recently, it was found that bacterial and eukaryotic transcripts are capped with cellular cofactors installed by their respective RNA polymerases (RNAPs) during transcription initiation. We now show that mitochondrial RNAP efficiently caps transcripts with ADP – containing cofactors. However, a functional role of universal RNAP – catalysed capping is not yet clear.

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