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RNA capping by mitochondrial and multi-subunit RNA polymerases

Recently, it was found that bacterial and eukaryotic transcripts are capped with cellular cofactors installed by their respective RNA polymerases (RNAPs) during transcription initiation. We now show that mitochondrial RNAP efficiently caps transcripts with ADP – containing cofactors. However, a func...

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Detalles Bibliográficos
Autores principales: Julius, Christina, Riaz-Bradley, Amber, Yuzenkova, Yulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150613/
https://www.ncbi.nlm.nih.gov/pubmed/29624107
http://dx.doi.org/10.1080/21541264.2018.1456258
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author Julius, Christina
Riaz-Bradley, Amber
Yuzenkova, Yulia
author_facet Julius, Christina
Riaz-Bradley, Amber
Yuzenkova, Yulia
author_sort Julius, Christina
collection PubMed
description Recently, it was found that bacterial and eukaryotic transcripts are capped with cellular cofactors installed by their respective RNA polymerases (RNAPs) during transcription initiation. We now show that mitochondrial RNAP efficiently caps transcripts with ADP – containing cofactors. However, a functional role of universal RNAP – catalysed capping is not yet clear.
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spelling pubmed-61506132018-09-24 RNA capping by mitochondrial and multi-subunit RNA polymerases Julius, Christina Riaz-Bradley, Amber Yuzenkova, Yulia Transcription Point-of-View Recently, it was found that bacterial and eukaryotic transcripts are capped with cellular cofactors installed by their respective RNA polymerases (RNAPs) during transcription initiation. We now show that mitochondrial RNAP efficiently caps transcripts with ADP – containing cofactors. However, a functional role of universal RNAP – catalysed capping is not yet clear. Taylor & Francis 2018-04-25 /pmc/articles/PMC6150613/ /pubmed/29624107 http://dx.doi.org/10.1080/21541264.2018.1456258 Text en © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Point-of-View
Julius, Christina
Riaz-Bradley, Amber
Yuzenkova, Yulia
RNA capping by mitochondrial and multi-subunit RNA polymerases
title RNA capping by mitochondrial and multi-subunit RNA polymerases
title_full RNA capping by mitochondrial and multi-subunit RNA polymerases
title_fullStr RNA capping by mitochondrial and multi-subunit RNA polymerases
title_full_unstemmed RNA capping by mitochondrial and multi-subunit RNA polymerases
title_short RNA capping by mitochondrial and multi-subunit RNA polymerases
title_sort rna capping by mitochondrial and multi-subunit rna polymerases
topic Point-of-View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150613/
https://www.ncbi.nlm.nih.gov/pubmed/29624107
http://dx.doi.org/10.1080/21541264.2018.1456258
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