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RNA capping by mitochondrial and multi-subunit RNA polymerases
Recently, it was found that bacterial and eukaryotic transcripts are capped with cellular cofactors installed by their respective RNA polymerases (RNAPs) during transcription initiation. We now show that mitochondrial RNAP efficiently caps transcripts with ADP – containing cofactors. However, a func...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150613/ https://www.ncbi.nlm.nih.gov/pubmed/29624107 http://dx.doi.org/10.1080/21541264.2018.1456258 |
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author | Julius, Christina Riaz-Bradley, Amber Yuzenkova, Yulia |
author_facet | Julius, Christina Riaz-Bradley, Amber Yuzenkova, Yulia |
author_sort | Julius, Christina |
collection | PubMed |
description | Recently, it was found that bacterial and eukaryotic transcripts are capped with cellular cofactors installed by their respective RNA polymerases (RNAPs) during transcription initiation. We now show that mitochondrial RNAP efficiently caps transcripts with ADP – containing cofactors. However, a functional role of universal RNAP – catalysed capping is not yet clear. |
format | Online Article Text |
id | pubmed-6150613 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-61506132018-09-24 RNA capping by mitochondrial and multi-subunit RNA polymerases Julius, Christina Riaz-Bradley, Amber Yuzenkova, Yulia Transcription Point-of-View Recently, it was found that bacterial and eukaryotic transcripts are capped with cellular cofactors installed by their respective RNA polymerases (RNAPs) during transcription initiation. We now show that mitochondrial RNAP efficiently caps transcripts with ADP – containing cofactors. However, a functional role of universal RNAP – catalysed capping is not yet clear. Taylor & Francis 2018-04-25 /pmc/articles/PMC6150613/ /pubmed/29624107 http://dx.doi.org/10.1080/21541264.2018.1456258 Text en © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Point-of-View Julius, Christina Riaz-Bradley, Amber Yuzenkova, Yulia RNA capping by mitochondrial and multi-subunit RNA polymerases |
title | RNA capping by mitochondrial and multi-subunit RNA polymerases |
title_full | RNA capping by mitochondrial and multi-subunit RNA polymerases |
title_fullStr | RNA capping by mitochondrial and multi-subunit RNA polymerases |
title_full_unstemmed | RNA capping by mitochondrial and multi-subunit RNA polymerases |
title_short | RNA capping by mitochondrial and multi-subunit RNA polymerases |
title_sort | rna capping by mitochondrial and multi-subunit rna polymerases |
topic | Point-of-View |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150613/ https://www.ncbi.nlm.nih.gov/pubmed/29624107 http://dx.doi.org/10.1080/21541264.2018.1456258 |
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