Real-Time Conformational Changes and Controlled Orientation of Native Proteins Inside a Protein Nanoreactor

[Image: see text] Protein conformations play crucial roles in most, if not all, biological processes. Here we show that the current carried through a nanopore by ions allows monitoring conformational changes of single and native substrate-binding domains (SBD) of an ATP-Binding Cassette importer in...

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Detalles Bibliográficos
Autores principales: Van Meervelt, Veerle, Soskine, Misha, Singh, Shubham, Schuurman-Wolters, Gea K., Wijma, Hein J., Poolman, Bert, Maglia, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150693/
https://www.ncbi.nlm.nih.gov/pubmed/29206456
http://dx.doi.org/10.1021/jacs.7b10106

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