Primary Splenic Diffuse Large B-Cell Lymphoma: A Rare Case of Massive Splenomegaly and Thrombocytopenia

Primary splenic diffuse large B-cell lymphoma (DLBCL) is a rare type of non-Hodgkin’s lymphoma. It often presents with abdominal pain or splenomegaly. We present a case of a 68-year-old male who presented to the emergency department with left sided abdominal pain. Workup revealed massive splenomegal...

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Detalles Bibliográficos
Autores principales: Khalid, Sidra, Daw, Jad H, Daw, Hamed, Haddad, Abdo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150744/
https://www.ncbi.nlm.nih.gov/pubmed/30254815
http://dx.doi.org/10.7759/cureus.3026
Descripción
Sumario:Primary splenic diffuse large B-cell lymphoma (DLBCL) is a rare type of non-Hodgkin’s lymphoma. It often presents with abdominal pain or splenomegaly. We present a case of a 68-year-old male who presented to the emergency department with left sided abdominal pain. Workup revealed massive splenomegaly and thrombocytopenia. A splenic biopsy confirmed the diagnosis of primary splenic DLBCL. The patient was treated with chemotherapy. This case highlights the importance of considering primary splenic DLBCL with splenomegaly and treating it with chemotherapy and/or splenectomy.

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