Primary Splenic Diffuse Large B-Cell Lymphoma: A Rare Case of Massive Splenomegaly and Thrombocytopenia

Primary splenic diffuse large B-cell lymphoma (DLBCL) is a rare type of non-Hodgkin’s lymphoma. It often presents with abdominal pain or splenomegaly. We present a case of a 68-year-old male who presented to the emergency department with left sided abdominal pain. Workup revealed massive splenomegal...

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Autores principales: Khalid, Sidra, Daw, Jad H, Daw, Hamed, Haddad, Abdo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150744/
https://www.ncbi.nlm.nih.gov/pubmed/30254815
http://dx.doi.org/10.7759/cureus.3026
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author Khalid, Sidra
Daw, Jad H
Daw, Hamed
Haddad, Abdo
author_facet Khalid, Sidra
Daw, Jad H
Daw, Hamed
Haddad, Abdo
author_sort Khalid, Sidra
collection PubMed
description Primary splenic diffuse large B-cell lymphoma (DLBCL) is a rare type of non-Hodgkin’s lymphoma. It often presents with abdominal pain or splenomegaly. We present a case of a 68-year-old male who presented to the emergency department with left sided abdominal pain. Workup revealed massive splenomegaly and thrombocytopenia. A splenic biopsy confirmed the diagnosis of primary splenic DLBCL. The patient was treated with chemotherapy. This case highlights the importance of considering primary splenic DLBCL with splenomegaly and treating it with chemotherapy and/or splenectomy.
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spelling pubmed-61507442018-09-25 Primary Splenic Diffuse Large B-Cell Lymphoma: A Rare Case of Massive Splenomegaly and Thrombocytopenia Khalid, Sidra Daw, Jad H Daw, Hamed Haddad, Abdo Cureus Internal Medicine Primary splenic diffuse large B-cell lymphoma (DLBCL) is a rare type of non-Hodgkin’s lymphoma. It often presents with abdominal pain or splenomegaly. We present a case of a 68-year-old male who presented to the emergency department with left sided abdominal pain. Workup revealed massive splenomegaly and thrombocytopenia. A splenic biopsy confirmed the diagnosis of primary splenic DLBCL. The patient was treated with chemotherapy. This case highlights the importance of considering primary splenic DLBCL with splenomegaly and treating it with chemotherapy and/or splenectomy. Cureus 2018-07-22 /pmc/articles/PMC6150744/ /pubmed/30254815 http://dx.doi.org/10.7759/cureus.3026 Text en Copyright © 2018, Khalid et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Khalid, Sidra
Daw, Jad H
Daw, Hamed
Haddad, Abdo
Primary Splenic Diffuse Large B-Cell Lymphoma: A Rare Case of Massive Splenomegaly and Thrombocytopenia
title Primary Splenic Diffuse Large B-Cell Lymphoma: A Rare Case of Massive Splenomegaly and Thrombocytopenia
title_full Primary Splenic Diffuse Large B-Cell Lymphoma: A Rare Case of Massive Splenomegaly and Thrombocytopenia
title_fullStr Primary Splenic Diffuse Large B-Cell Lymphoma: A Rare Case of Massive Splenomegaly and Thrombocytopenia
title_full_unstemmed Primary Splenic Diffuse Large B-Cell Lymphoma: A Rare Case of Massive Splenomegaly and Thrombocytopenia
title_short Primary Splenic Diffuse Large B-Cell Lymphoma: A Rare Case of Massive Splenomegaly and Thrombocytopenia
title_sort primary splenic diffuse large b-cell lymphoma: a rare case of massive splenomegaly and thrombocytopenia
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150744/
https://www.ncbi.nlm.nih.gov/pubmed/30254815
http://dx.doi.org/10.7759/cureus.3026
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