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Progressive multiple sequence alignment with indel evolution

BACKGROUND: Sequence alignment is crucial in genomics studies. However, optimal multiple sequence alignment (MSA) is NP-hard. Thus, modern MSA methods employ progressive heuristics, breaking the problem into a series of pairwise alignments guided by a phylogeny. Changes between homologous characters...

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Detalles Bibliográficos
Autores principales:	Maiolo, Massimo, Zhang, Xiaolei, Gil, Manuel, Anisimova, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151001/ https://www.ncbi.nlm.nih.gov/pubmed/30241460 http://dx.doi.org/10.1186/s12859-018-2357-1

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