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Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study

OBJECTIVE: To compare clinical outcomes in laparoscopic and open radical hysterectomy with pelvic lymphadenectomy (LRH) in early cervical cancer without the selection bias. METHODS: One special retrospective study was conducted with more than 400 patients involved in laparoscopic procedure. RESULTS:...

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Autores principales: Guo, Jianfeng, Yang, Lu, Cai, Jing, Xu, Linjuan, Min, Jie, Shen, Yi, Xiong, Zhoufang, Dong, Weihong, Bunyamanop, Vichitra, Wang, Zehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151097/
https://www.ncbi.nlm.nih.gov/pubmed/30271174
http://dx.doi.org/10.2147/OTT.S156064
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author Guo, Jianfeng
Yang, Lu
Cai, Jing
Xu, Linjuan
Min, Jie
Shen, Yi
Xiong, Zhoufang
Dong, Weihong
Bunyamanop, Vichitra
Wang, Zehua
author_facet Guo, Jianfeng
Yang, Lu
Cai, Jing
Xu, Linjuan
Min, Jie
Shen, Yi
Xiong, Zhoufang
Dong, Weihong
Bunyamanop, Vichitra
Wang, Zehua
author_sort Guo, Jianfeng
collection PubMed
description OBJECTIVE: To compare clinical outcomes in laparoscopic and open radical hysterectomy with pelvic lymphadenectomy (LRH) in early cervical cancer without the selection bias. METHODS: One special retrospective study was conducted with more than 400 patients involved in laparoscopic procedure. RESULTS: Our results suggest that estimated blood loss and transfusion requirements were significantly lower in the LRH group. Postoperative hospital stay was also significantly shorter in the LRH group. Significant difference was found in the number of pelvic lymph nodes retrieved between the LRH and open radical hysterectomy with pelvic lymphadenectomy (ORH) groups. There were no differences in operating time, perioperative complications, progression-free survival, and overall survival between the LRH and ORH groups. CONCLUSION: LRH can be considered a safe and effective alternative to conventional open surgery (ORH) for early-stage cervical cancer.
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spelling pubmed-61510972018-09-28 Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study Guo, Jianfeng Yang, Lu Cai, Jing Xu, Linjuan Min, Jie Shen, Yi Xiong, Zhoufang Dong, Weihong Bunyamanop, Vichitra Wang, Zehua Onco Targets Ther Original Research OBJECTIVE: To compare clinical outcomes in laparoscopic and open radical hysterectomy with pelvic lymphadenectomy (LRH) in early cervical cancer without the selection bias. METHODS: One special retrospective study was conducted with more than 400 patients involved in laparoscopic procedure. RESULTS: Our results suggest that estimated blood loss and transfusion requirements were significantly lower in the LRH group. Postoperative hospital stay was also significantly shorter in the LRH group. Significant difference was found in the number of pelvic lymph nodes retrieved between the LRH and open radical hysterectomy with pelvic lymphadenectomy (ORH) groups. There were no differences in operating time, perioperative complications, progression-free survival, and overall survival between the LRH and ORH groups. CONCLUSION: LRH can be considered a safe and effective alternative to conventional open surgery (ORH) for early-stage cervical cancer. Dove Medical Press 2018-09-18 /pmc/articles/PMC6151097/ /pubmed/30271174 http://dx.doi.org/10.2147/OTT.S156064 Text en © 2018 Guo et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Guo, Jianfeng
Yang, Lu
Cai, Jing
Xu, Linjuan
Min, Jie
Shen, Yi
Xiong, Zhoufang
Dong, Weihong
Bunyamanop, Vichitra
Wang, Zehua
Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study
title Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study
title_full Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study
title_fullStr Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study
title_full_unstemmed Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study
title_short Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study
title_sort laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151097/
https://www.ncbi.nlm.nih.gov/pubmed/30271174
http://dx.doi.org/10.2147/OTT.S156064
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