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Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study
OBJECTIVE: To compare clinical outcomes in laparoscopic and open radical hysterectomy with pelvic lymphadenectomy (LRH) in early cervical cancer without the selection bias. METHODS: One special retrospective study was conducted with more than 400 patients involved in laparoscopic procedure. RESULTS:...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151097/ https://www.ncbi.nlm.nih.gov/pubmed/30271174 http://dx.doi.org/10.2147/OTT.S156064 |
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author | Guo, Jianfeng Yang, Lu Cai, Jing Xu, Linjuan Min, Jie Shen, Yi Xiong, Zhoufang Dong, Weihong Bunyamanop, Vichitra Wang, Zehua |
author_facet | Guo, Jianfeng Yang, Lu Cai, Jing Xu, Linjuan Min, Jie Shen, Yi Xiong, Zhoufang Dong, Weihong Bunyamanop, Vichitra Wang, Zehua |
author_sort | Guo, Jianfeng |
collection | PubMed |
description | OBJECTIVE: To compare clinical outcomes in laparoscopic and open radical hysterectomy with pelvic lymphadenectomy (LRH) in early cervical cancer without the selection bias. METHODS: One special retrospective study was conducted with more than 400 patients involved in laparoscopic procedure. RESULTS: Our results suggest that estimated blood loss and transfusion requirements were significantly lower in the LRH group. Postoperative hospital stay was also significantly shorter in the LRH group. Significant difference was found in the number of pelvic lymph nodes retrieved between the LRH and open radical hysterectomy with pelvic lymphadenectomy (ORH) groups. There were no differences in operating time, perioperative complications, progression-free survival, and overall survival between the LRH and ORH groups. CONCLUSION: LRH can be considered a safe and effective alternative to conventional open surgery (ORH) for early-stage cervical cancer. |
format | Online Article Text |
id | pubmed-6151097 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-61510972018-09-28 Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study Guo, Jianfeng Yang, Lu Cai, Jing Xu, Linjuan Min, Jie Shen, Yi Xiong, Zhoufang Dong, Weihong Bunyamanop, Vichitra Wang, Zehua Onco Targets Ther Original Research OBJECTIVE: To compare clinical outcomes in laparoscopic and open radical hysterectomy with pelvic lymphadenectomy (LRH) in early cervical cancer without the selection bias. METHODS: One special retrospective study was conducted with more than 400 patients involved in laparoscopic procedure. RESULTS: Our results suggest that estimated blood loss and transfusion requirements were significantly lower in the LRH group. Postoperative hospital stay was also significantly shorter in the LRH group. Significant difference was found in the number of pelvic lymph nodes retrieved between the LRH and open radical hysterectomy with pelvic lymphadenectomy (ORH) groups. There were no differences in operating time, perioperative complications, progression-free survival, and overall survival between the LRH and ORH groups. CONCLUSION: LRH can be considered a safe and effective alternative to conventional open surgery (ORH) for early-stage cervical cancer. Dove Medical Press 2018-09-18 /pmc/articles/PMC6151097/ /pubmed/30271174 http://dx.doi.org/10.2147/OTT.S156064 Text en © 2018 Guo et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Guo, Jianfeng Yang, Lu Cai, Jing Xu, Linjuan Min, Jie Shen, Yi Xiong, Zhoufang Dong, Weihong Bunyamanop, Vichitra Wang, Zehua Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study |
title | Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study |
title_full | Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study |
title_fullStr | Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study |
title_full_unstemmed | Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study |
title_short | Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study |
title_sort | laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151097/ https://www.ncbi.nlm.nih.gov/pubmed/30271174 http://dx.doi.org/10.2147/OTT.S156064 |
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