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Targeting the MALAT1/PARP1/LIG3 complex induces DNA damage and apoptosis in multiple myeloma

Metastasis-associated lung adenocarcinoma transcript 1(MALAT1) is a highly conserved long non-coding RNA (lncRNA). Overexpression of MALAT1 has been demonstrated to related to poor prognosis of multiple myeloma(MM) patients. Here, we demonstrated that MALAT1 plays important roles in MM DNA repair an...

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Detalles Bibliográficos
Autores principales:	Hu, Yi, Lin, Jianhong, Fang, Hua, Fang, Jing, Li, Chen, Chen, Wei, Liu, Shuang, Ondrejka, Sarah, Gong, Zihua, Reu, Frederic, Maciejewski, Jaroslaw, Yi, Qing, Zhao, Jian-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151178/ https://www.ncbi.nlm.nih.gov/pubmed/29632340 http://dx.doi.org/10.1038/s41375-018-0104-2

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