Cargando…
Therapeutic implications of how TNF links apolipoprotein E, phosphorylated tau, α‐synuclein, amyloid‐β and insulin resistance in neurodegenerative diseases
While cytokines such as TNF have long been recognized as essential to normal cerebral physiology, the implications of their chronic excessive production within the brain are now also increasingly appreciated. Syndromes as diverse as malaria and lead poisoning, as well as non‐infectious neurodegenera...
Autores principales: | Clark, I A, Vissel, B |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151331/ https://www.ncbi.nlm.nih.gov/pubmed/30097997 http://dx.doi.org/10.1111/bph.14471 |
Ejemplares similares
-
Excess cerebral TNF causing glutamate excitotoxicity rationalizes treatment of neurodegenerative diseases and neurogenic pain by anti-TNF agents
por: Clark, Ian A., et al.
Publicado: (2016) -
The Role of α-Synuclein and LRRK2 in Tau Phosphorylation
por: Kawakami, Fumitaka, et al.
Publicado: (2015) -
Revisiting the Impact of Neurodegenerative Proteins in Epilepsy: Focus on Alpha-Synuclein, Beta-Amyloid, and Tau
por: Paudel, Yam Nath, et al.
Publicado: (2020) -
Inflammation-sleep interface in brain disease: TNF, insulin, orexin
por: Clark, Ian A, et al.
Publicado: (2014) -
Cross-Linked α-Synuclein as Inhibitor of Amyloid Formation
por: Murvai, Nikoletta, et al.
Publicado: (2023)