Cargando…

Anti-Inflammatory Pyranochalcone Derivative Attenuates LPS-Induced Acute Kidney Injury via Inhibiting TLR4/NF-κB Pathway

Treatment of septic acute kidney injury (AKI) has still been beyond satisfaction, although anti-inflammatory therapy is beneficial for sepsis-induced AKI. Compound 5b was derived from natural pyranochalcones and exhibited potent anti-inflammatory activity in adjuvant-induced arthritis. In this study...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Min, Zeng, Xiaoxi, Guo, Fan, Huang, Rongshuang, Feng, Yanhuan, Ma, Liang, Zhou, Li, Fu, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151422/ https://www.ncbi.nlm.nih.gov/pubmed/28994737 http://dx.doi.org/10.3390/molecules22101683

Ejemplares similares

NF-κB inhibition attenuates LPS-induced TLR4 activation in monocyte cells
por: Wan, Jian, et al.
Publicado: (2016)

Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathway
por: Badshah, Haroon, et al.
Publicado: (2016)

Anti-Inflammatory Effects of Camellia fascicularis Polyphenols via Attenuation of NF-κB and MAPK Pathways in LPS-Induced THP-1 Macrophages
por: Gao, Miaozi, et al.
Publicado: (2022)

Prolactin decreases LPS-induced inflammatory cytokines by inhibiting TLR-4/NFκB signaling in the human placenta
por: Olmos-Ortiz, A, et al.
Publicado: (2019)

Negative Regulation of Tec Kinase Alleviates LPS-Induced Acute Kidney Injury in Mice via theTLR4/NF-κB Signaling Pathway
por: Zhang, Wei, et al.
Publicado: (2020)

The Role of Autophagy in Kidney Inflammatory Injury via the NF-κB Route Induced by LPS
por: Wu, Yu, et al.
Publicado: (2015)

Lianqinjiedu decoction attenuates LPS-induced inflammation and acute lung injury in rats via TLR4/NF-κB pathway
por: Deng, Guiming, et al.
Publicado: (2017)

Inhibition of Fatty Acid–Binding Protein 4 Attenuated Kidney Fibrosis by Mediating Macrophage-to-Myofibroblast Transition
por: Feng, Yanhuan, et al.
Publicado: (2020)

Recognition of LPS by TLR4: Potential for Anti-Inflammatory Therapies
por: Nijland, Reindert, et al.
Publicado: (2014)

METTL3 Attenuates LPS-Induced Inflammatory Response in Macrophages via NF-κB Signaling Pathway
por: Wang, Jinghua, et al.
Publicado: (2019)

Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling
por: Muhammad, Tahir, et al.
Publicado: (2019)

Ginseng Sprouts Attenuate Mortality and Systemic Inflammation by Modulating TLR4/NF-κB Signaling in an LPS-Induced Mouse Model of Sepsis
por: Hwang, Seung-Ju, et al.
Publicado: (2023)

Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice
por: Qi, Shuang, et al.
Publicado: (2020)

Chondroprotective and anti‐inflammatory effects of amurensin H by regulating TLR4/Syk/NF‐κB signals
por: Ma, Pei, et al.
Publicado: (2019)

ISGylation Inhibits an LPS-Induced Inflammatory Response via the TLR4/NF-κB Signaling Pathway in Goat Endometrial Epithelial Cells
por: Xiao, Jinbang, et al.
Publicado: (2021)

The TLR4/NFκB-Dependent Inflammatory Response Activated by LPS Is Inhibited in Human Macrophages Pre-Exposed to Amorphous Silica Nanoparticles
por: Bianchi, Massimiliano G., et al.
Publicado: (2022)

Anti-inflammatory effects of guggulsterone on murine macrophage by inhibiting LPS-induced inflammatory cytokines in NF-κB signaling pathway
por: Zhang, Jin-Hua, et al.
Publicado: (2016)

Inosine Pretreatment Attenuates LPS-Induced Lung Injury through Regulating the TLR4/MyD88/NF-κB Signaling Pathway In Vivo
por: Mao, Bingyong, et al.
Publicado: (2022)

Epiisopiloturine, an Alkaloid from Pilocarpus microphyllus, Attenuates LPS-Induced Neuroinflammation by Interfering in the TLR4/NF-κB-MAPK Signaling Pathway in Microglial Cells
por: de Sousa, João Antônio Costa, et al.
Publicado: (2023)

AICAR inhibits NFκB DNA binding independently of AMPK to attenuate LPS-triggered inflammatory responses in human macrophages
por: Kirchner, Johannes, et al.
Publicado: (2018)

Anti-Inflammatory Effect of Auranofin on Palmitic Acid and LPS-Induced Inflammatory Response by Modulating TLR4 and NOX4-Mediated NF-κB Signaling Pathway in RAW264.7 Macrophages
por: Hwangbo, Hyun, et al.
Publicado: (2021)

Knockdown of TRIM52 alleviates LPS-induced inflammatory injury in human periodontal ligament cells through the TLR4/NF-κB pathway
por: Liu, Peng, et al.
Publicado: (2020)

Daeshiho-tang attenuates inflammatory response and oxidative stress in LPS-stimulated macrophages by regulating TLR4/MyD88, NF-κB, MAPK, and Nrf2/HO-1 pathways
por: Oh, Yong Jin, et al.
Publicado: (2023)

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF
por: Fitzgerald, Katherine A., et al.
Publicado: (2003)

NRF2 Exerts Anti-Inflammatory Effects in LPS-Induced gEECs by Inhibiting the Activation of the NF-κB
por: Bao, Hongchu, et al.
Publicado: (2021)

Anti-Inflammatory Activity of Oligomeric Proanthocyanidins Via Inhibition of NF-κB and MAPK in LPS-Stimulated MAC-T Cells
por: Ma, Xiao, et al.
Publicado: (2020)

Okanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways
por: Hou, Yue, et al.
Publicado: (2017)

GBE50 Attenuates Inflammatory Response by Inhibiting the p38 MAPK and NF-κB Pathways in LPS-Stimulated Microglial Cells
por: He, Gai-ying, et al.
Publicado: (2014)

The Anti-Inflammatory Effect and Structure of EPCP1-2 from Crypthecodinium cohnii via Modulation of TLR4-NF-κB Pathways in LPS-Induced RAW 264.7 Cells
por: Ma, Xiaolei, et al.
Publicado: (2017)

Xuanfei Baidu Formula attenuates LPS-induced acute lung injury by inhibiting the NF-κB signaling pathway
por: Zhu, Yanru, et al.
Publicado: (2023)

Humanized anti-TLR4 monoclonal antibody ameliorates lipopolysaccharide-related acute kidney injury by inhibiting TLR4/NF-κB signaling
por: Zhang, Qiuhua, et al.
Publicado: (2021)

(+)-JQ1 attenuated LPS-induced microglial inflammation via MAPK/NFκB signaling
por: Wang, Huanhuan, et al.
Publicado: (2018)

Metformin attenuates LPS-induced neuronal injury and cognitive impairments by blocking NF-κB pathway
por: Zhou, Chenliang, et al.
Publicado: (2021)

Berberine attenuates septic cardiomyopathy by inhibiting TLR4/NF-κB signalling in rats
por: Chen, Huiqi, et al.
Publicado: (2021)

Coral-Derived Endophytic Fungal Product, Butyrolactone-I, Alleviates Lps Induced Intestinal Epithelial Cell Inflammatory Response Through TLR4/NF-κB and MAPK Signaling Pathways: An in vitro and in vivo Studies
por: Chen, Shengwei, et al.
Publicado: (2021)

2-methylquinazoline derivative F7 as a potent and selective HDAC6 inhibitor protected against rhabdomyolysis-induced acute kidney injury
por: Liu, Jing, et al.
Publicado: (2019)

Abrogating ClC-3 Inhibits LPS-induced Inflammation via Blocking the TLR4/NF-κB Pathway
por: Xiang, Nan-lin, et al.
Publicado: (2016)

Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis
por: Qu, Yifan, et al.
Publicado: (2021)

Tacrolimus alleviates LPS‐induced AKI by inhibiting TLR4/MyD88/NF‐κB signalling in mice
por: Hu, Xueqing, et al.
Publicado: (2021)

CETP Lowers TLR4 Expression Which Attenuates the Inflammatory Response Induced by LPS and Polymicrobial Sepsis
por: Venancio, Tatiana Martins, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_dpgu0jho45hk06lluusftvgcur