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The Recognition of Calmodulin to the Target Sequence of Calcineurin—A Novel Binding Mode

Calcineurin (CaN) is a Ca(2+)/calmodulin-dependent Ser/Thr protein phosphatase, which plays essential roles in many cellular and developmental processes. CaN comprises two subunits, a catalytic subunit (CaN-A, 60 kDa) and a regulatory subunit (CaN-B, 19 kDa). CaN-A tightly binds to CaN-B in the pres...

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Detalles Bibliográficos
Autores principales: Chyan, Chia-Lin, Irene, Deli, Lin, Sin-Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151454/
https://www.ncbi.nlm.nih.gov/pubmed/28934144
http://dx.doi.org/10.3390/molecules22101584