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Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials
In recent years innovative nanostructures are attracting increasing interest and, among them, dendrimers have shown several fields of application. Dendrimers can be designed and modified in plentiful ways giving rise to hundreds of different molecules with specific characteristics and functionalitie...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151464/ https://www.ncbi.nlm.nih.gov/pubmed/28934169 http://dx.doi.org/10.3390/molecules22101581 |
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author | García-Gallego, Sandra Franci, Gianluigi Falanga, Annarita Gómez, Rafael Folliero, Veronica Galdiero, Stefania de la Mata, Francisco Javier Galdiero, Massimiliano |
author_facet | García-Gallego, Sandra Franci, Gianluigi Falanga, Annarita Gómez, Rafael Folliero, Veronica Galdiero, Stefania de la Mata, Francisco Javier Galdiero, Massimiliano |
author_sort | García-Gallego, Sandra |
collection | PubMed |
description | In recent years innovative nanostructures are attracting increasing interest and, among them, dendrimers have shown several fields of application. Dendrimers can be designed and modified in plentiful ways giving rise to hundreds of different molecules with specific characteristics and functionalities. Biomedicine is probably the field where these molecules find extraordinary applicability, and this is probably due to their multi-valency and to the fact that several other chemicals can be coupled to them to obtain desired compounds. In this review we will describe the different production strategies and the tools and technologies for the study of their characteristics. Finally, we provide a panoramic overview of their applications to meet biomedical needs, especially their use as novel antimicrobials. |
format | Online Article Text |
id | pubmed-6151464 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61514642018-11-13 Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials García-Gallego, Sandra Franci, Gianluigi Falanga, Annarita Gómez, Rafael Folliero, Veronica Galdiero, Stefania de la Mata, Francisco Javier Galdiero, Massimiliano Molecules Review In recent years innovative nanostructures are attracting increasing interest and, among them, dendrimers have shown several fields of application. Dendrimers can be designed and modified in plentiful ways giving rise to hundreds of different molecules with specific characteristics and functionalities. Biomedicine is probably the field where these molecules find extraordinary applicability, and this is probably due to their multi-valency and to the fact that several other chemicals can be coupled to them to obtain desired compounds. In this review we will describe the different production strategies and the tools and technologies for the study of their characteristics. Finally, we provide a panoramic overview of their applications to meet biomedical needs, especially their use as novel antimicrobials. MDPI 2017-09-21 /pmc/articles/PMC6151464/ /pubmed/28934169 http://dx.doi.org/10.3390/molecules22101581 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review García-Gallego, Sandra Franci, Gianluigi Falanga, Annarita Gómez, Rafael Folliero, Veronica Galdiero, Stefania de la Mata, Francisco Javier Galdiero, Massimiliano Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials |
title | Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials |
title_full | Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials |
title_fullStr | Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials |
title_full_unstemmed | Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials |
title_short | Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials |
title_sort | function oriented molecular design: dendrimers as novel antimicrobials |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151464/ https://www.ncbi.nlm.nih.gov/pubmed/28934169 http://dx.doi.org/10.3390/molecules22101581 |
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