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Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials

In recent years innovative nanostructures are attracting increasing interest and, among them, dendrimers have shown several fields of application. Dendrimers can be designed and modified in plentiful ways giving rise to hundreds of different molecules with specific characteristics and functionalitie...

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Autores principales: García-Gallego, Sandra, Franci, Gianluigi, Falanga, Annarita, Gómez, Rafael, Folliero, Veronica, Galdiero, Stefania, de la Mata, Francisco Javier, Galdiero, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151464/
https://www.ncbi.nlm.nih.gov/pubmed/28934169
http://dx.doi.org/10.3390/molecules22101581
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author García-Gallego, Sandra
Franci, Gianluigi
Falanga, Annarita
Gómez, Rafael
Folliero, Veronica
Galdiero, Stefania
de la Mata, Francisco Javier
Galdiero, Massimiliano
author_facet García-Gallego, Sandra
Franci, Gianluigi
Falanga, Annarita
Gómez, Rafael
Folliero, Veronica
Galdiero, Stefania
de la Mata, Francisco Javier
Galdiero, Massimiliano
author_sort García-Gallego, Sandra
collection PubMed
description In recent years innovative nanostructures are attracting increasing interest and, among them, dendrimers have shown several fields of application. Dendrimers can be designed and modified in plentiful ways giving rise to hundreds of different molecules with specific characteristics and functionalities. Biomedicine is probably the field where these molecules find extraordinary applicability, and this is probably due to their multi-valency and to the fact that several other chemicals can be coupled to them to obtain desired compounds. In this review we will describe the different production strategies and the tools and technologies for the study of their characteristics. Finally, we provide a panoramic overview of their applications to meet biomedical needs, especially their use as novel antimicrobials.
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spelling pubmed-61514642018-11-13 Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials García-Gallego, Sandra Franci, Gianluigi Falanga, Annarita Gómez, Rafael Folliero, Veronica Galdiero, Stefania de la Mata, Francisco Javier Galdiero, Massimiliano Molecules Review In recent years innovative nanostructures are attracting increasing interest and, among them, dendrimers have shown several fields of application. Dendrimers can be designed and modified in plentiful ways giving rise to hundreds of different molecules with specific characteristics and functionalities. Biomedicine is probably the field where these molecules find extraordinary applicability, and this is probably due to their multi-valency and to the fact that several other chemicals can be coupled to them to obtain desired compounds. In this review we will describe the different production strategies and the tools and technologies for the study of their characteristics. Finally, we provide a panoramic overview of their applications to meet biomedical needs, especially their use as novel antimicrobials. MDPI 2017-09-21 /pmc/articles/PMC6151464/ /pubmed/28934169 http://dx.doi.org/10.3390/molecules22101581 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
García-Gallego, Sandra
Franci, Gianluigi
Falanga, Annarita
Gómez, Rafael
Folliero, Veronica
Galdiero, Stefania
de la Mata, Francisco Javier
Galdiero, Massimiliano
Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials
title Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials
title_full Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials
title_fullStr Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials
title_full_unstemmed Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials
title_short Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials
title_sort function oriented molecular design: dendrimers as novel antimicrobials
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151464/
https://www.ncbi.nlm.nih.gov/pubmed/28934169
http://dx.doi.org/10.3390/molecules22101581
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