Cargando…

Ginsenoside Rg3 Prevents Oxidative Stress-Induced Astrocytic Senescence and Ameliorates Senescence Paracrine Effects on Glioblastoma

Senescent astrocytes in aging brain express senescence-associated secretory phenotype (SASP) and link with increased brain aging and its related diseases. In order to determine whether ginsenosides ameliorate the astrocytic senescence in vitro, human astrocytic CRT cells and primary rat astrocytes w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hou, Jingang, Kim, Sunchang, Sung, Changkeun, Choi, Chulhee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151485/ https://www.ncbi.nlm.nih.gov/pubmed/28891967 http://dx.doi.org/10.3390/molecules22091516

Ejemplares similares

Ginsenoside F1-Mediated Telomere Preservation Delays Cellular Senescence
por: Hou, Jingang, et al.
Publicado: (2023)

D-galactose induces astrocytic aging and contributes to astrocytoma progression and chemoresistance via cellular senescence
por: Hou, Jingang, et al.
Publicado: (2019)

High fat diet-induced brain damaging effects through autophagy-mediated senescence, inflammation and apoptosis mitigated by ginsenoside F1-enhanced mixture
por: Hou, Jingang, et al.
Publicado: (2022)

Ginsenoside Rg1 Prevents Cognitive Impairment and Hippocampus Senescence in a Rat Model of D-Galactose-Induced Aging
por: Zhu, Jiahong, et al.
Publicado: (2014)

Ginsenoside Rg1 ameliorates testicular senescence changes in D-gal-induced aging mice via anti-inflammatory and antioxidative mechanisms
por: Wang, Zi-Ling, et al.
Publicado: (2018)

Ginsenoside Rg1 supplementation clears senescence-associated β-galactosidase in exercising human skeletal muscle
por: Wu, Jinfu, et al.
Publicado: (2019)

Activation of Ca(2+)‐AMPK‐mediated autophagy by ginsenoside Rg3 attenuates cellular senescence in human dermal fibroblasts
por: Kim, Dasol, et al.
Publicado: (2021)

Proteomic analyses reveal that ginsenoside Rg3(S) partially reverses cellular senescence in human dermal fibroblasts by inducing peroxiredoxin
por: Jang, Ik-Soon, et al.
Publicado: (2020)

Ginsenoside Rg3 ameliorates allergic airway inflammation and oxidative stress in mice
por: Huang, Wen-Chung, et al.
Publicado: (2021)

20(S)-ginsenoside Rg3 promotes senescence and apoptosis in gallbladder cancer cells via the p53 pathway
por: Zhang, Fei, et al.
Publicado: (2015)

Ginsenoside Rg3 inhibits the senescence of prostate stromal cells through down-regulation of interleukin 8 expression
por: Peng, Yanfei, et al.
Publicado: (2017)

Ginsenoside Rg1 ameliorates apoptosis, senescence and oxidative stress in ox-LDL-induced vascular endothelial cells via the AMPK/SIRT3/p53 signaling pathway
por: Lyu, Tian-Jiao, et al.
Publicado: (2022)

Ginsenoside Rh2 mitigates doxorubicin‐induced cardiotoxicity by inhibiting apoptotic and inflammatory damage and weakening pathological remodelling in breast cancer‐bearing mice
por: Hou, Jingang, et al.
Publicado: (2022)

Paracrine roles of cellular senescence in promoting tumourigenesis
por: Gonzalez-Meljem, Jose Mario, et al.
Publicado: (2018)

20(S)-Ginsenoside Rg3 Promotes Senescence And Apoptosis In Gallbladder Cancer Cells Via The P53 Pathway [Corrigendum]
Publicado: (2019)

Effects of Ginsenoside Rg1 Regulating Wnt/β-Catenin Signaling on Neural Stem Cells to Delay Brain Senescence
por: Xiang, Yue, et al.
Publicado: (2019)

Ginsenoside Rg1 ameliorates cardiac oxidative stress and inflammation in streptozotocin-induced diabetic rats
por: Qin, Qiaoji, et al.
Publicado: (2019)

Stereoisomer-specific ginsenoside 20(S)-Rg3 reverses replicative senescence of human diploid fibroblasts via Akt-mTOR-Sirtuin signaling
por: Yang, Kyeong-Eun, et al.
Publicado: (2020)

Ginsenoside Rg1 promotes astrocyte‐to‐neuron transdifferentiation in rat and its possible mechanism
por: Shen, Kelv, et al.
Publicado: (2022)

Novel Antidepressant Mechanism of Ginsenoside Rg1 in Regulating the Dysfunction of the Glutamatergic System in Astrocytes
por: Zhang, Ningning, et al.
Publicado: (2022)

Astrocyte senescence: Evidence and significance
por: Cohen, Justin, et al.
Publicado: (2019)

Paracrine cellular senescence exacerbates biliary injury and impairs regeneration
por: Ferreira-Gonzalez, Sofia, et al.
Publicado: (2018)

Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy
por: Wang, Ni, et al.
Publicado: (2023)

Ginsenoside RG1 enhances the paracrine effects of bone marrow-derived mesenchymal stem cells on radiation induced intestinal injury
por: Luo, Yujun, et al.
Publicado: (2020)

Ginsenoside Rg5 Ameliorates Cisplatin-Induced Nephrotoxicity in Mice through Inhibition of Inflammation, Oxidative Stress, and Apoptosis
por: Li, Wei, et al.
Publicado: (2016)

Role of Senescent Astrocytes in Health and Disease
por: Meldolesi, Jacopo
Publicado: (2023)

Ginsenoside Rg1 Improves Differentiation by Inhibiting Senescence of Human Bone Marrow Mesenchymal Stem Cell via GSK-3β and β-Catenin
por: Wang, Ziling, et al.
Publicado: (2020)

A complex secretory program orchestrated by the inflammasome controls paracrine senescence
por: Acosta, Juan Carlos, et al.
Publicado: (2013)

Adamantinomatous craniopharyngioma as a model to understand paracrine and senescence-induced tumourigenesis
por: Gonzalez-Meljem, Jose Mario, et al.
Publicado: (2021)

Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner
por: Lagnado, Anthony, et al.
Publicado: (2021)

SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response
por: Tsuji, Shunya, et al.
Publicado: (2022)

Ginsenoside Rg3 Ameliorates Stress of Broiler Chicks Induced by Escherichia coli Lipopolysaccharide
por: Bi, Shicheng, et al.
Publicado: (2022)

Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence
por: Crowe, Elizabeth P., et al.
Publicado: (2016)

Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1
por: Vo, Hoang Tung, et al.
Publicado: (2015)

Astrocyte Senescence as a Component of Alzheimer’s Disease
por: Bhat, Rekha, et al.
Publicado: (2012)

Astrocyte Senescence and Alzheimer’s Disease: A Review
por: Han, Xiaojuan, et al.
Publicado: (2020)

Ginsenoside Rg1 Ameliorates Neuroinflammation via Suppression of Connexin43 Ubiquitination to Attenuate Depression
por: Wang, Huiqin, et al.
Publicado: (2021)

Anti-Angiogenic Properties of Ginsenoside Rg3
por: Nakhjavani, Maryam, et al.
Publicado: (2020)

Pharmacological activities of ginsenoside Rg5 (Review)
por: Liu, Ming-Yang, et al.
Publicado: (2021)

Comparative Pharmacokinetics of Ginsenoside Rg(3) and Ginsenoside Rh(2) after Oral Administration of Ginsenoside Rg(3) in Normal and Walker 256 Tumor-bearing Rats
por: Fan, He, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_sebbbpk9te8g7fsqniag70jklr