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In Vitro Evaluation of Third Generation PAMAM Dendrimer Conjugates

The present study compares the use of high generation G3 and low generation G0 Polyamidoamine (PAMAM) dendrimers as drug carriers of naproxen (NAP), a poorly water soluble drug. Naproxen was conjugated to G3 in different ratios and to G0 in a 1:1 ratio via a diethylene glycol linker. A lauroyl chain...

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Detalles Bibliográficos
Autores principales: Najlah, Mohammad, Freeman, Sally, Khoder, Mouhamad, Attwood, David, D’Emanuele, Antony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151491/
https://www.ncbi.nlm.nih.gov/pubmed/28976921
http://dx.doi.org/10.3390/molecules22101661