Cargando…

Evaluation of LPS-Induced Acute Lung Injury Attenuation in Rats by Aminothiazole-Paeonol Derivatives

Paeonol is a key phenolic compound in the root bark of Moutan Cortex Radicis that has been used in traditional Chinese Medicine to ameliorate inflammation. A series of aminothiazole-paeonol derivatives (APDs) were synthesized in this work and subjected to preliminary evaluation in cells followed by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Pin-Kuei, Yang, Chi-Yu, Huang, Su-Chin, Hung, Yu-Wen, Jeng, Kee-Ching, Huang, Ying-Pei, Chuang, Hong, Huang, Nai-Chun, Li, Jui-Ping, Hsu, Ming-Hua, Chen, Jen-Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151495/ https://www.ncbi.nlm.nih.gov/pubmed/28946699 http://dx.doi.org/10.3390/molecules22101605

Ejemplares similares

Synthesis and Evaluation of Aminothiazole-Paeonol Derivatives as Potential Anticancer Agents
por: Tsai, Chia-Ying, et al.
Publicado: (2016)

Anti-Inflammatory and Anticoagulative Effects of Paeonol on LPS-Induced Acute Lung Injury in Rats
por: Fu, Pin-Kuei, et al.
Publicado: (2012)

Aminothiazoles inhibit RANKL‐ and LPS‐mediated osteoclastogenesis and PGE (2) production in RAW 264.7 cells
por: Kats, Anna, et al.
Publicado: (2016)

Paeonol attenuates inflammation-mediated neurotoxicity and microglial activation
por: Nam, Kyong Nyon, et al.
Publicado: (2013)

Paeonol attenuates inflammation by confining HMGB1 to the nucleus
por: Miao, Jifei, et al.
Publicado: (2021)

Corylin protects LPS-induced sepsis and attenuates LPS-induced inflammatory response
por: Hung, Yung-Li, et al.
Publicado: (2017)

Paeonol Attenuates Cigarette Smoke-Induced Lung Inflammation by Inhibiting ROS-Sensitive Inflammatory Signaling
por: Liu, Meng-Han, et al.
Publicado: (2014)

Characterization of Novel α-Mangostin and Paeonol Derivatives With Cancer-Selective Cytotoxicity
por: Nunna, Suneetha, et al.
Publicado: (2022)

Paeonol Attenuates Quorum-Sensing Regulated Virulence and Biofilm Formation in Pseudomonas aeruginosa
por: Yang, Dan, et al.
Publicado: (2021)

Paeonol Protects Memory after Ischemic Stroke via Inhibiting β-Secretase and Apoptosis
por: Su, Shan-Yu, et al.
Publicado: (2012)

Effects of Paeonol on Anti-Neuroinflammatory Responses in Microglial Cells
por: Lin, Chingju, et al.
Publicado: (2015)

Synthesis and antifungal activity of benzimidazole, benzotriazole and aminothiazole derivatives
por: Khabnadideh, S., et al.
Publicado: (2012)

Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents
por: Kesicki, Edward A., et al.
Publicado: (2016)

Identification of Enolase as the Target of 2-Aminothiazoles in Mycobacterium tuberculosis
por: Wescott, Heather H., et al.
Publicado: (2018)

QSAR study of anti-prion activity of 2-aminothiazoles
por: Mandi, Prasit, et al.
Publicado: (2012)

Development of Paeonol Liposomes: Design, Optimization, in vitro and in vivo Evaluation
por: Huang, Shan, et al.
Publicado: (2022)

Pharmacokinetics, Tissue Distribution and Excretion of Paeonol and Its Major Metabolites in Rats Provide a Further Insight Into Paeonol Effectiveness
por: Hu, Xintong, et al.
Publicado: (2020)

Attenuating Oxidative Stress by Paeonol Protected against Acetaminophen-Induced Hepatotoxicity in Mice
por: Ding, Yi, et al.
Publicado: (2016)

A review on therapeutical potential of paeonol in atherosclerosis
por: Yu, Wei, et al.
Publicado: (2022)

Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p
por: Mei, Liyan, et al.
Publicado: (2019)

Antitrypanosomal activity of 5-nitro-2-aminothiazole-based compounds
por: Papadopoulou, Maria V., et al.
Publicado: (2016)

Paeonol Attenuated Vascular Fibrosis Through Regulating Treg/Th17 Balance in a Gut Microbiota-Dependent Manner
por: Shi, Xiaoyan, et al.
Publicado: (2021)

Nordalbergin Exerts Anti-Neuroinflammatory Effects by Attenuating MAPK Signaling Pathway, NLRP3 Inflammasome Activation and ROS Production in LPS-Stimulated BV2 Microglia
por: Lo, Jung, et al.
Publicado: (2023)

A one-pot electrochemical synthesis of 2-aminothiazoles from active methylene ketones and thioureas mediated by NH(4)I
por: Yang, Shang-Feng, et al.
Publicado: (2022)

Paeonol, a Major Compound of Moutan Cortex, Attenuates Cisplatin-Induced Nephrotoxicity in Mice
por: Lee, Hyojung, et al.
Publicado: (2013)

Paeonol Protects Against Myocardial Ischemia/Reperfusion-Induced Injury by Mediating Apoptosis and Autophagy Crosstalk
por: Tsai, Chin-Feng, et al.
Publicado: (2021)

Mycotoxin Zearalenone Attenuates Innate Immune Responses and Suppresses NLRP3 Inflammasome Activation in LPS-Activated Macrophages
por: Lee, Po-Yen, et al.
Publicado: (2021)

Bis(2-aminothiazole-4-acetato)aquazinc(II)
por: Zhang, Lai-Jun, et al.
Publicado: (2009)

Development and therapeutic potential of 2-aminothiazole derivatives in anticancer drug discovery
por: Alizadeh, Seyedeh Roya, et al.
Publicado: (2021)

Synthesis of Novel Aminothiazole Derivatives as Promising Antiviral, Antioxidant and Antibacterial Candidates
por: Minickaitė, Rūta, et al.
Publicado: (2022)

Punicalagin Attenuates LPS-Induced Inflammation and ROS Production in Microglia by Inhibiting the MAPK/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation
por: Lo, Jung, et al.
Publicado: (2022)

Paeonol attenuates retinopathy in streptozotocin-induced diabetes in rats by regulating the oxidative stress and polyol pathway
por: Adki, Kaveri M., et al.
Publicado: (2022)

Corylin inhibits LPS-induced inflammatory response and attenuates the activation of NLRP3 inflammasome in microglia
por: Huang, Ming-Yii, et al.
Publicado: (2018)

Paeonol Ameliorates Glucose and Lipid Metabolism in Experimental Diabetes by Activating Akt
por: Xu, Futian, et al.
Publicado: (2019)

An Overview on Synthetic 2-Aminothiazole-Based Compounds Associated with Four Biological Activities
por: Farouk Elsadek, Mohamed, et al.
Publicado: (2021)

Role of Paeonol in an Astrocyte Model of Parkinson’s Disease
por: Ye, Maosheng, et al.
Publicado: (2017)

Beneficial Effects Exerted by Paeonol in the Management of Atherosclerosis
por: Lu, Li, et al.
Publicado: (2018)

Modulating Effect of Paeonol on Piglets With Ulcerative Colitis
por: Wang, Shanshan, et al.
Publicado: (2022)

Review of the Protective Mechanism of Paeonol on Cardiovascular Disease
por: Yang, Chunkun, et al.
Publicado: (2023)

Paeonol Protects Rat Heart by Improving Regional Blood Perfusion during No-Reflow
por: Ma, Lina, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_n8p4qr69gnnjc4t309mhum811e