An Unusual Dimeric Inhibitor of Acetylcholinesterase: Cooperative Binding of Crystal Violet

Acetylcholinesterase (AChE) is an essential enzyme that terminates cholinergic transmission by a rapid hydrolysis of the neurotransmitter acetylcholine. AChE is an important target for treatment of various cholinergic deficiencies, including Alzheimer’s disease and myasthenia gravis. In a previous h...

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Detalles Bibliográficos
Autores principales: Allgardsson, Anders, David Andersson, C., Akfur, Christine, Worek, Franz, Linusson, Anna, Ekström, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151500/
https://www.ncbi.nlm.nih.gov/pubmed/28867801
http://dx.doi.org/10.3390/molecules22091433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151500/
https://www.ncbi.nlm.nih.gov/pubmed/28867801
http://dx.doi.org/10.3390/molecules22091433

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