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Emodin Inhibition of Influenza A Virus Replication and Influenza Viral Pneumonia via the Nrf2, TLR4, p38/JNK and NF-kappaB Pathways
Lasting activations of toll-like receptors (TLRs), MAPK and NF-κB pathways can support influenza A virus (IAV) infection and promote pneumonia. In this study, we have investigated the effect and mechanism of action of emodin on IAV infection using qRT-PCR, western blotting, ELISA, Nrf2 luciferase re...
Autores principales: | Dai, Jian-Ping, Wang, Qian-Wen, Su, Yun, Gu, Li-Ming, Zhao, Ying, Chen, Xiao-Xua, Chen, Cheng, Li, Wei-Zhong, Wang, Ge-Fei, Li, Kang-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151665/ https://www.ncbi.nlm.nih.gov/pubmed/29057806 http://dx.doi.org/10.3390/molecules22101754 |
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