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Ionic Liquid-Catalyzed Green Protocol for Multi-Component Synthesis of Dihydropyrano[2,3-c]pyrazoles as Potential Anticancer Scaffolds

A series of 6-amino-4-substituted-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles 5a–j were synthesized via one-pot, four-component condensation reactions of aryl aldehydes 1a–j, propanedinitrile (2), hydrazine hydrate (3) and ethyl acetoacetate (4) under solvent-free conditions. We report...

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Detalles Bibliográficos
Autores principales:	Nimbalkar, Urja D., Seijas, Julio A., Vazquez-Tato, Maria Pilar, Damale, Manoj G., Sangshetti, Jaiprakash N., Nikalje, Anna Pratima G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151819/ https://www.ncbi.nlm.nih.gov/pubmed/28956863 http://dx.doi.org/10.3390/molecules22101628

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