Cargando…

Knockdown of POLE2 expression suppresses lung adenocarcinoma cell malignant phenotypes in vitro

In the present study, we profiled β-elemene-regulated gene expression and investigated the effects of the silencing of the DNA polymerase epsilon 2, accessory subunit (POLE2) in lung cancer cells. Differently expressed genes were profiled in A549 cells incubated in the presence or absence of β-eleme...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jianying, Wang, Juanhong, Yu, Jun, Zhao, Yuling, Dong, Ya, Fan, Yali, Li, Namiao, Zhang, Yingying, Wang, Yili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151888/ https://www.ncbi.nlm.nih.gov/pubmed/30132567 http://dx.doi.org/10.3892/or.2018.6659

Ejemplares similares

Ku80 gene knockdown by the CRISPR/Cas9 technique affects the biological functions of human thyroid carcinoma cells
por: Fan, Yali, et al.
Publicado: (2019)

Knockdown of GALNT1 suppresses malignant phenotype of hepatocellular carcinoma by suppressing EGFR signaling
por: Huang, Miao-Juei, et al.
Publicado: (2015)

Chemoprotective effect of atorvastatin against benzo(a)pyrene-induced lung cancer via the inhibition of oxidative stress and inflammatory parameters
por: Du, Xusheng, et al.
Publicado: (2021)

POLE2 knockdown reduce tumorigenesis in esophageal squamous cells
por: Zhu, Yongjun, et al.
Publicado: (2020)

Annexin A3 Knockdown Suppresses Lung Adenocarcinoma
por: Liu, Ying-Fu, et al.
Publicado: (2016)

Kynureninase knockdown inhibits cisplatin resistance in vivo and in vitro and impacts the prognosis of cervical adenocarcinoma
por: Zhang, Jun-wen, et al.
Publicado: (2023)

Knockdown of PKM2 Suppresses Tumor Growth and Invasion in Lung Adenocarcinoma
por: Sun, Hong, et al.
Publicado: (2015)

Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells
por: Lin, Weiguo, et al.
Publicado: (2020)

Knockdown of LGR5 suppresses the proliferation of glioma cells in vitro and in vivo
por: WANG, DONGLIANG, et al.
Publicado: (2014)

Knockdown of ISOC1 suppresses cell proliferation in pancreatic cancer in vitro
por: Cheng, Li, et al.
Publicado: (2019)

Knockdown of PREX2a inhibits the malignant phenotype of glioma cells
por: Liu, Liang, et al.
Publicado: (2021)

Knockdown of LRRN1 inhibits malignant phenotypes through the regulation of HIF-1α/Notch pathway in pancreatic ductal adenocarcinoma
por: Zhang, Yalu, et al.
Publicado: (2021)

Phenotype of POLE-mutated endometrial cancer
por: Imboden, Sara, et al.
Publicado: (2019)

Knockdown of PREX2a inhibits the malignant phenotype of osteosarcoma cells
por: Dai, Zixun, et al.
Publicado: (2022)

Knockdown of spindle pole body component 25 homolog inhibits cell proliferation and cycle progression in prostate cancer
por: Cui, Feilun, et al.
Publicado: (2018)

PSMC2 knockdown suppressed tumor progression of skin cutaneous melanoma
por: Yang, Yanwen, et al.
Publicado: (2021)

Knockdown of SLC39A7 suppresses cell proliferation, migration and invasion in cervical cancer
por: Wei, Yongqing, et al.
Publicado: (2017)

Knockdown of ANXA1 suppresses the biological behavior of human NSCLC cells in vitro
por: FANG, YING, et al.
Publicado: (2016)

POLE2 facilitates the malignant phenotypes of glioblastoma through promoting AURKA-mediated stabilization of FOXM1
por: Zhang, Peng, et al.
Publicado: (2022)

SMC1A knockdown induces growth suppression of human lung adenocarcinoma cells through G1/S cell cycle phase arrest and apoptosis pathways in vitro
por: ZHANG, YI-FAN, et al.
Publicado: (2013)

Anti-silencing function 1B knockdown suppresses the malignant phenotype of colorectal cancer by inactivating the phosphatidylinositol 3-kinase/AKT pathway
por: Yu, Gen-Hua, et al.
Publicado: (2022)

Knockdown of SMAD3 inhibits the growth and enhances the radiosensitivity of lung adenocarcinoma via p21 in vitro and in vivo
por: Niu, Hao, et al.
Publicado: (2020)

Knockdown of TRPM8 Suppresses Cancer Malignancy and Enhances Epirubicin-induced Apoptosis in Human Osteosarcoma Cells
por: Wang, Yongzhi, et al.
Publicado: (2013)

Monoacylglycerol Lipase Knockdown Inhibits Cell Proliferation and Metastasis in Lung Adenocarcinoma
por: Zhang, Hao, et al.
Publicado: (2020)

Berberine Inhibits FOXM1 Dependent Transcriptional Regulation of POLE2 and Interferes With the Survival of Lung Adenocarcinoma
por: Ni, Lulu, et al.
Publicado: (2022)

Knockdown of HE4 suppresses aggressive cell growth and malignant progression of ovarian cancer by inhibiting the JAK/STAT3 pathway
por: Wang, Aihong, et al.
Publicado: (2019)

Knockdown of TRAF3IP2 suppresses the expression of VEGFA and the proliferation of keratinocytes and vascular endothelial cells
por: Song, Yali, et al.
Publicado: (2019)

Knockdown of CDCA5 suppresses malignant progression of breast cancer cells by regulating PDS5A
por: Wang, Yang, et al.
Publicado: (2022)

TXNDC9 knockdown inhibits lung adenocarcinoma progression by targeting YWHAG
por: Wang, Jing, et al.
Publicado: (2022)

In vitro knockdown of TsDNase II-7 suppresses Trichinella spiralis invasion into the host’s intestinal epithelial cells
por: Wang, Jing, et al.
Publicado: (2023)

Knockdown of BCL6 Inhibited Malignant Phenotype and Enhanced Sensitivity of Glioblastoma Cells to TMZ through AKT Pathway
por: Song, Wen, et al.
Publicado: (2018)

Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression
por: Yang, Fang, et al.
Publicado: (2021)

Silencing the long noncoding RNA, TINCR, a molecular sponge of miR-335, inhibits the malignant phenotype of epithelial ovarian cancer via FGF2 suppression
por: Li, Rui, et al.
Publicado: (2022)

ANP32A Knockdown Attenuates the Malignant Biological Behavior of Colorectal Cancer Cells by Suppressing Epithelial-mesenchymal Transition and ERK Activation
por: Li, Xiaojuan, et al.
Publicado: (2023)

CCT6A knockdown suppresses osteosarcoma cell growth and Akt pathway activation in vitro
por: Zeng, Weiquan, et al.
Publicado: (2022)

A mutation in POLE predisposing to a multi-tumour phenotype
por: ROHLIN, ANNA, et al.
Publicado: (2014)

RRM2 silencing suppresses malignant phenotype and enhances radiosensitivity via activating cGAS/STING signaling pathway in lung adenocarcinoma
por: Jiang, Xueping, et al.
Publicado: (2021)

MMP-1 is overexpressed in triple-negative breast cancer tissues and the knockdown of MMP-1 expression inhibits tumor cell malignant behaviors in vitro
por: Wang, Qi-Min, et al.
Publicado: (2019)

HSP60-knockdown suppresses proliferation in colorectal cancer cells via activating the adenine/AMPK/mTOR signaling pathway
por: Guo, Jianying, et al.
Publicado: (2021)

Up‐regulation of CDHR5 expression promotes malignant phenotype of pancreatic ductal adenocarcinoma
por: Gao, Junyi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_222cjt5dcc77p0qso9e7k7ds3j